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Astrocyte activation in the periaqueductal gray promotes descending facilitation to cancer-induced bone pain through the JNK MAPK signaling pathway

Descending nociceptive modulation from the supraspinal structures has an important role in cancer-induced bone pain (CIBP). Midbrain ventrolateral periaqueductal gray (vlPAG) is a critical component of descending nociceptive circuits; nevertheless, its precise cellular and molecular mechanisms invol...

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Detalles Bibliográficos
Autores principales:	Ni, Hua-dong, Xu, Long Sheng, Wang, Yungong, Li, Hongbo, An, Kang, Liu, Mingjuan, Liu, Qianying, Deng, Houshen, He, Qiuli, Huang, Bing, Fang, Jianqiao, Yao, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388461/ https://www.ncbi.nlm.nih.gov/pubmed/30700204 http://dx.doi.org/10.1177/1744806919831909

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