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Usnea Acid as Multidrug Resistance (MDR) Reversing Agent against Human Chronic Myelogenous Leukemia K562/ADR Cells via an ROS Dependent Apoptosis

PURPOSE: Multidrug resistance (MDR) is a major obstacle in chemotherapy of leukemia treatments. In this paper, we investigated Usnea Acid (UA) as MDR reversal agent on hematologic K562/ADR cells via ROS dependent apoptosis. METHODS: CCK8 assay was used to measure cell viability rate of K562/ADR. Int...

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Detalles Bibliográficos
Autores principales:	Wang, Wenjing, Niu, Shubin, Qiao, Luxin, Wei, Feili, Yin, Jiming, Wang, Shanshan, Ouyang, Yabo, Chen, Dexi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388510/ https://www.ncbi.nlm.nih.gov/pubmed/30886864 http://dx.doi.org/10.1155/2019/8727935

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