Previously Diagnosed Leber’s Hereditary Optic Neuropathy with Clinical Signs of Idiopathic Intracranial Hypertension Responsive to Acetazolamide Therapy

PURPOSE: To present a case of suspected Leber's hereditary optic neuropathy (LHON) with MRI and OCT findings compatible with pseudotumor cerebri responsive to acetazolamide therapy. CASE REPORT: A five-year-old boy referred to our clinic with optic atrophy and low vision was originally diagnose...

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Autores principales: Sajjadi, Hamid, Poorsalman, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388523/
https://www.ncbi.nlm.nih.gov/pubmed/30820297
http://dx.doi.org/10.4103/jovr.jovr_85_18
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author Sajjadi, Hamid
Poorsalman, Hossein
author_facet Sajjadi, Hamid
Poorsalman, Hossein
author_sort Sajjadi, Hamid
collection PubMed
description PURPOSE: To present a case of suspected Leber's hereditary optic neuropathy (LHON) with MRI and OCT findings compatible with pseudotumor cerebri responsive to acetazolamide therapy. CASE REPORT: A five-year-old boy referred to our clinic with optic atrophy and low vision was originally diagnosed with LHON. Laboratory tests were negative for LHON, while OCT and MRI were consistent with pseudotumor cerebri. Acetazolamide therapy resulted in dramatic improvement of visual acuity. CONCLUSION: Some cases of previously labeled hereditary optic neuropathies with clinical signs of idiopathic intracranial hypertension could respond to intracranial pressure lowering treatment.
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spelling pubmed-63885232019-02-28 Previously Diagnosed Leber’s Hereditary Optic Neuropathy with Clinical Signs of Idiopathic Intracranial Hypertension Responsive to Acetazolamide Therapy Sajjadi, Hamid Poorsalman, Hossein J Ophthalmic Vis Res Case Report PURPOSE: To present a case of suspected Leber's hereditary optic neuropathy (LHON) with MRI and OCT findings compatible with pseudotumor cerebri responsive to acetazolamide therapy. CASE REPORT: A five-year-old boy referred to our clinic with optic atrophy and low vision was originally diagnosed with LHON. Laboratory tests were negative for LHON, while OCT and MRI were consistent with pseudotumor cerebri. Acetazolamide therapy resulted in dramatic improvement of visual acuity. CONCLUSION: Some cases of previously labeled hereditary optic neuropathies with clinical signs of idiopathic intracranial hypertension could respond to intracranial pressure lowering treatment. Medknow Publications & Media Pvt Ltd 2019 /pmc/articles/PMC6388523/ /pubmed/30820297 http://dx.doi.org/10.4103/jovr.jovr_85_18 Text en Copyright: © 2019 Journal of Ophthalmic and Vision Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Sajjadi, Hamid
Poorsalman, Hossein
Previously Diagnosed Leber’s Hereditary Optic Neuropathy with Clinical Signs of Idiopathic Intracranial Hypertension Responsive to Acetazolamide Therapy
title Previously Diagnosed Leber’s Hereditary Optic Neuropathy with Clinical Signs of Idiopathic Intracranial Hypertension Responsive to Acetazolamide Therapy
title_full Previously Diagnosed Leber’s Hereditary Optic Neuropathy with Clinical Signs of Idiopathic Intracranial Hypertension Responsive to Acetazolamide Therapy
title_fullStr Previously Diagnosed Leber’s Hereditary Optic Neuropathy with Clinical Signs of Idiopathic Intracranial Hypertension Responsive to Acetazolamide Therapy
title_full_unstemmed Previously Diagnosed Leber’s Hereditary Optic Neuropathy with Clinical Signs of Idiopathic Intracranial Hypertension Responsive to Acetazolamide Therapy
title_short Previously Diagnosed Leber’s Hereditary Optic Neuropathy with Clinical Signs of Idiopathic Intracranial Hypertension Responsive to Acetazolamide Therapy
title_sort previously diagnosed leber’s hereditary optic neuropathy with clinical signs of idiopathic intracranial hypertension responsive to acetazolamide therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388523/
https://www.ncbi.nlm.nih.gov/pubmed/30820297
http://dx.doi.org/10.4103/jovr.jovr_85_18
work_keys_str_mv AT sajjadihamid previouslydiagnosedlebershereditaryopticneuropathywithclinicalsignsofidiopathicintracranialhypertensionresponsivetoacetazolamidetherapy
AT poorsalmanhossein previouslydiagnosedlebershereditaryopticneuropathywithclinicalsignsofidiopathicintracranialhypertensionresponsivetoacetazolamidetherapy

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