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Standardized, Scalable, and Timely Flexible Adeno-Associated Virus Vector Production Using Frozen High-Density HEK-293 Cell Stocks and CELLdiscs

Adeno-associated virus (AAV) vectors currently represent the most attractive platform for viral gene therapy and are also valuable research tools to study gene function or establish disease models. Consequently, many academic labs, core facilities, and biotech/pharma companies meanwhile produce AAVs...

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Detalles Bibliográficos
Autores principales: Strobel, Benjamin, Zuckschwerdt, Kai, Zimmermann, Gudrun, Mayer, Christine, Eytner, Ruth, Rechtsteiner, Philipp, Kreuz, Sebastian, Lamla, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388714/
https://www.ncbi.nlm.nih.gov/pubmed/30693792
http://dx.doi.org/10.1089/hgtb.2018.228