Starch nanoparticles for delivery of the histone deacetylase inhibitor CG-1521 in breast cancer treatment

BACKGROUND: The efficacy of epigenetic drugs, such as histone deacetylase inhibitors, is often diminished by poor aqueous solubility resulting in limited bioavailability and a low therapeutic index. To overcome the suboptimal therapeutic index, we have developed a biocompatible starch nanoparticle f...

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Detalles Bibliográficos
Autores principales: Alp, Esma, Damkaci, Fehmi, Guven, Eylem, Tenniswood, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388755/
https://www.ncbi.nlm.nih.gov/pubmed/30863064
http://dx.doi.org/10.2147/IJN.S191837

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