Current and emerging biomarkers of frailty in the elderly

The term “frailty” is used to describe a subset of older adults who appear weaker and more vulnerable than their age-matched counterparts, despite having similar comorbidities, demography, sex, and age. The diagnosis of frailty is usually clinical and based on specific criteria, which are sometimes...

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Detalles Bibliográficos
Autores principales: Saedi, Ahmed Al, Feehan, Jack, Phu, Steven, Duque, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388773/
https://www.ncbi.nlm.nih.gov/pubmed/30863033
http://dx.doi.org/10.2147/CIA.S168687
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author Saedi, Ahmed Al
Feehan, Jack
Phu, Steven
Duque, Gustavo
author_facet Saedi, Ahmed Al
Feehan, Jack
Phu, Steven
Duque, Gustavo
author_sort Saedi, Ahmed Al
collection PubMed
description The term “frailty” is used to describe a subset of older adults who appear weaker and more vulnerable than their age-matched counterparts, despite having similar comorbidities, demography, sex, and age. The diagnosis of frailty is usually clinical and based on specific criteria, which are sometimes inconsistent. Therefore, there is an increasing need to identify and validate robust biomarkers for this condition. In this review, we summarize current evidence on the validity and practicality of the most commonly used biomarkers for frailty, while also comparing them with new upcoming strategies to identify this condition.
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spelling pubmed-63887732019-03-12 Current and emerging biomarkers of frailty in the elderly Saedi, Ahmed Al Feehan, Jack Phu, Steven Duque, Gustavo Clin Interv Aging Review The term “frailty” is used to describe a subset of older adults who appear weaker and more vulnerable than their age-matched counterparts, despite having similar comorbidities, demography, sex, and age. The diagnosis of frailty is usually clinical and based on specific criteria, which are sometimes inconsistent. Therefore, there is an increasing need to identify and validate robust biomarkers for this condition. In this review, we summarize current evidence on the validity and practicality of the most commonly used biomarkers for frailty, while also comparing them with new upcoming strategies to identify this condition. Dove Medical Press 2019-02-19 /pmc/articles/PMC6388773/ /pubmed/30863033 http://dx.doi.org/10.2147/CIA.S168687 Text en © 2019 Al Saedi et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Saedi, Ahmed Al
Feehan, Jack
Phu, Steven
Duque, Gustavo
Current and emerging biomarkers of frailty in the elderly
title Current and emerging biomarkers of frailty in the elderly
title_full Current and emerging biomarkers of frailty in the elderly
title_fullStr Current and emerging biomarkers of frailty in the elderly
title_full_unstemmed Current and emerging biomarkers of frailty in the elderly
title_short Current and emerging biomarkers of frailty in the elderly
title_sort current and emerging biomarkers of frailty in the elderly
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388773/
https://www.ncbi.nlm.nih.gov/pubmed/30863033
http://dx.doi.org/10.2147/CIA.S168687
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