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Neisseria gonorrhoeae evades autophagic killing by downregulating CD46-cyt1 and remodeling lysosomes

The Gram-negative human pathogen N. gonorrhoeae (Ngo) quickly attaches to epithelial cells, and large numbers of the bacteria remain on the cell surface for prolonged periods. Ngo invades cells but few viable intracellular bacteria are recovered until later stages of infection, leading to the assump...

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Detalles Bibliográficos
Autores principales: Kim, Won J., Mai, Annette, Weyand, Nathan J., Rendón, Maria A., Van Doorslaer, Koenraad, So, Magdalene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388937/
https://www.ncbi.nlm.nih.gov/pubmed/30753248
http://dx.doi.org/10.1371/journal.ppat.1007495