DNA methylation-mediated Klotho silencing is an independent prognostic biomarker of head and neck squamous carcinoma

PURPOSE: To study the prognostic value of klotho (KL) and its promoter DNA methylation in head and neck squamous cell carcinoma (HNSCC) and to assess their associations with the autophagy gene LC3 and the RNA transferase gene NSUN2. MATERIALS AND METHODS: Upper quartile normalized RNA-seq V2 RSEM va...

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Detalles Bibliográficos
Autores principales: Zhu, Yun, Cao, Xuehong, Zhang, Xiaomeng, Chen, Quan, Wen, Lei, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388988/
https://www.ncbi.nlm.nih.gov/pubmed/30863149
http://dx.doi.org/10.2147/CMAR.S188415

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