Brain metastases from breast cancer may respond to endocrine therapy: report of two cases

Brain metastases from breast cancer have a poor prognosis. There have been few cases reported where patients with breast cancer and brain metastases respond well to endocrine therapy (tamoxifen or letrozole). Here, we report the cases of two breast cancer patients with brain metastases who responded...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Sun, Bing, Liu, Chao, Shi, Sanzhong, Ding, Lijuan, Liu, Jiannan, Wu, Shikai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389012/
https://www.ncbi.nlm.nih.gov/pubmed/30863105
http://dx.doi.org/10.2147/OTT.S188143
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author Wang, Qian
Sun, Bing
Liu, Chao
Shi, Sanzhong
Ding, Lijuan
Liu, Jiannan
Wu, Shikai
author_facet Wang, Qian
Sun, Bing
Liu, Chao
Shi, Sanzhong
Ding, Lijuan
Liu, Jiannan
Wu, Shikai
author_sort Wang, Qian
collection PubMed
description Brain metastases from breast cancer have a poor prognosis. There have been few cases reported where patients with breast cancer and brain metastases respond well to endocrine therapy (tamoxifen or letrozole). Here, we report the cases of two breast cancer patients with brain metastases who responded to medroxyprogesterone acetate and fulvestrant, respectively. These cases indicate that endocrine therapy could be very effective in the management of brain metastases from breast carcinoma.
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spelling pubmed-63890122019-03-12 Brain metastases from breast cancer may respond to endocrine therapy: report of two cases Wang, Qian Sun, Bing Liu, Chao Shi, Sanzhong Ding, Lijuan Liu, Jiannan Wu, Shikai Onco Targets Ther Case Series Brain metastases from breast cancer have a poor prognosis. There have been few cases reported where patients with breast cancer and brain metastases respond well to endocrine therapy (tamoxifen or letrozole). Here, we report the cases of two breast cancer patients with brain metastases who responded to medroxyprogesterone acetate and fulvestrant, respectively. These cases indicate that endocrine therapy could be very effective in the management of brain metastases from breast carcinoma. Dove Medical Press 2019-02-19 /pmc/articles/PMC6389012/ /pubmed/30863105 http://dx.doi.org/10.2147/OTT.S188143 Text en © 2019 Wang et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Series
Wang, Qian
Sun, Bing
Liu, Chao
Shi, Sanzhong
Ding, Lijuan
Liu, Jiannan
Wu, Shikai
Brain metastases from breast cancer may respond to endocrine therapy: report of two cases
title Brain metastases from breast cancer may respond to endocrine therapy: report of two cases
title_full Brain metastases from breast cancer may respond to endocrine therapy: report of two cases
title_fullStr Brain metastases from breast cancer may respond to endocrine therapy: report of two cases
title_full_unstemmed Brain metastases from breast cancer may respond to endocrine therapy: report of two cases
title_short Brain metastases from breast cancer may respond to endocrine therapy: report of two cases
title_sort brain metastases from breast cancer may respond to endocrine therapy: report of two cases
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389012/
https://www.ncbi.nlm.nih.gov/pubmed/30863105
http://dx.doi.org/10.2147/OTT.S188143
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