Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration

A 35-year-old male underwent open-heart surgery and required multiple blood product transfusions. Citrate, a preservative in blood products, caused serum ionized calcium chelation leading to hypocalcemia, a prolonged corrected QT (QTc) interval, and separate episodes of ventricular fibrillation and...

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Detalles Bibliográficos
Autores principales: Mosebach, Christian M, Kluger, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Cardiac/Thoracic/Vascular Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389027/
https://www.ncbi.nlm.nih.gov/pubmed/30820384
http://dx.doi.org/10.7759/cureus.3765
Descripción
Sumario:A 35-year-old male underwent open-heart surgery and required multiple blood product transfusions. Citrate, a preservative in blood products, caused serum ionized calcium chelation leading to hypocalcemia, a prolonged corrected QT (QTc) interval, and separate episodes of ventricular fibrillation and torsades de pointes (TdP). This case highlights an uncommon complication of blood product transfusion-induced hypocalcemia with precipitant arrhythmia.

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