Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration

A 35-year-old male underwent open-heart surgery and required multiple blood product transfusions. Citrate, a preservative in blood products, caused serum ionized calcium chelation leading to hypocalcemia, a prolonged corrected QT (QTc) interval, and separate episodes of ventricular fibrillation and...

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Detalles Bibliográficos
Autores principales: Mosebach, Christian M, Kluger, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Cardiac/Thoracic/Vascular Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389027/
https://www.ncbi.nlm.nih.gov/pubmed/30820384
http://dx.doi.org/10.7759/cureus.3765
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author Mosebach, Christian M
Kluger, Jeffrey
author_facet Mosebach, Christian M
Kluger, Jeffrey
author_sort Mosebach, Christian M
collection PubMed
description A 35-year-old male underwent open-heart surgery and required multiple blood product transfusions. Citrate, a preservative in blood products, caused serum ionized calcium chelation leading to hypocalcemia, a prolonged corrected QT (QTc) interval, and separate episodes of ventricular fibrillation and torsades de pointes (TdP). This case highlights an uncommon complication of blood product transfusion-induced hypocalcemia with precipitant arrhythmia.
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spelling pubmed-63890272019-02-28 Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration Mosebach, Christian M Kluger, Jeffrey Cureus Cardiac/Thoracic/Vascular Surgery A 35-year-old male underwent open-heart surgery and required multiple blood product transfusions. Citrate, a preservative in blood products, caused serum ionized calcium chelation leading to hypocalcemia, a prolonged corrected QT (QTc) interval, and separate episodes of ventricular fibrillation and torsades de pointes (TdP). This case highlights an uncommon complication of blood product transfusion-induced hypocalcemia with precipitant arrhythmia. Cureus 2018-12-21 /pmc/articles/PMC6389027/ /pubmed/30820384 http://dx.doi.org/10.7759/cureus.3765 Text en Copyright © 2018, Mosebach et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiac/Thoracic/Vascular Surgery
Mosebach, Christian M
Kluger, Jeffrey
Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration
title Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration
title_full Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration
title_fullStr Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration
title_full_unstemmed Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration
title_short Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration
title_sort probable hypocalcemia induced ventricular fibrillation and torsades de pointes following blood product administration
topic Cardiac/Thoracic/Vascular Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389027/
https://www.ncbi.nlm.nih.gov/pubmed/30820384
http://dx.doi.org/10.7759/cureus.3765
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