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Heavy alcohol drinking downregulates ALDH2 gene expression but heavy smoking up-regulates SOD2 gene expression in head and neck squamous cell carcinoma

BACKGROUND: This study aims to determine the relationship between expression levels of ALDH2 and SOD2 genes and clinical parameters such as alcohol drinking, tobacco smoking, primary site of HNSCC, and human papilloma virus (HPV) state. METHODS: Gene expression data were obtained from gene expressio...

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Detalles Bibliográficos
Autores principales: Lee, Dong Jin, Lee, Hyung Min, Kim, Jin Hwan, Park, II Seok, Rho, Young Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389042/
https://www.ncbi.nlm.nih.gov/pubmed/28841898
http://dx.doi.org/10.1186/s12957-017-1225-1

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