Mutations in BRCA1, BRCA2 and other breast and ovarian cancer susceptibility genes in Central and South American populations

Breast cancer (BC) is the most common malignancy among women worldwide. A major advance in the understanding of the genetic etiology of BC was the discovery of BRCA1 and BRCA2 (BRCA1/2) genes, which are considered high-penetrance BC genes. In non-carriers of BRCA1/2 mutations, disease susceptibility...

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Detalles Bibliográficos
Autores principales: Jara, Lilian, Morales, Sebastian, de Mayo, Tomas, Gonzalez-Hormazabal, Patricio, Carrasco, Valentina, Godoy, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389095/
https://www.ncbi.nlm.nih.gov/pubmed/28985766
http://dx.doi.org/10.1186/s40659-017-0139-2

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