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Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology
BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia in the elderly population. In this study, we used the APP/PS1 transgenic mouse model to explore the feasibility of using diffusion kurtosis imaging (DKI) as a tool for the early det...
Autores principales: | Praet, Jelle, Manyakov, Nikolay V., Muchene, Leacky, Mai, Zhenhua, Terzopoulos, Vasilis, de Backer, Steve, Torremans, An, Guns, Pieter-Jan, Van De Casteele, Tom, Bottelbergs, Astrid, Van Broeck, Bianca, Sijbers, Jan, Smeets, Dirk, Shkedy, Ziv, Bijnens, Luc, Pemberton, Darrel J., Schmidt, Mark E., Van der Linden, Annemie, Verhoye, Marleen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389136/ https://www.ncbi.nlm.nih.gov/pubmed/29370870 http://dx.doi.org/10.1186/s13195-017-0329-8 |
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