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HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses

BACKGROUND: Denervation triggers numerous molecular responses in skeletal muscle, including the activation of catabolic pathways and oxidative stress, leading to progressive muscle atrophy. Histone deacetylase 4 (HDAC4) mediates skeletal muscle response to denervation, suggesting the use of HDAC inh...

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Detalles Bibliográficos
Autores principales:	Pigna, Eva, Renzini, Alessandra, Greco, Emanuela, Simonazzi, Elena, Fulle, Stefania, Mancinelli, Rosa, Moresi, Viviana, Adamo, Sergio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389241/ https://www.ncbi.nlm.nih.gov/pubmed/29477142 http://dx.doi.org/10.1186/s13395-018-0153-2

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