Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function

EndoC-βH1 is emerging as a critical human β cell model to study the genetic and environmental etiologies of β cell (dys)function and diabetes. Comprehensive knowledge of its molecular landscape is lacking, yet required, for effective use of this model. Here, we report chromosomal (spectral karyotypi...

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Detalles Bibliográficos
Autores principales: Lawlor, Nathan, Márquez, Eladio J., Orchard, Peter, Narisu, Narisu, Shamim, Muhammad Saad, Thibodeau, Asa, Varshney, Arushi, Kursawe, Romy, Erdos, Michael R., Kanke, Matt, Gu, Huiya, Pak, Evgenia, Dutra, Amalia, Russell, Sheikh, Li, Xingwang, Piecuch, Emaly, Luo, Oscar, Chines, Peter S., Fuchbserger, Christian, Sethupathy, Praveen, Aiden, Aviva Presser, Ruan, Yijun, Aiden, Erez Lieberman, Collins, Francis S., Ucar, Duygu, Parker, Stephen C.J., Stitzel, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389269/
https://www.ncbi.nlm.nih.gov/pubmed/30650367
http://dx.doi.org/10.1016/j.celrep.2018.12.083

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