JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress

The restoration of homeostasis after tissue damage relies on proper spatial-temporal control of damage-induced apoptosis and compensatory proliferation. In Drosophila imaginal discs these processes are coordinated by the stress response pathway JNK. We demonstrate that JNK signaling induces a dose-d...

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Detalles Bibliográficos
Autores principales: Cosolo, Andrea, Jaiswal, Janhvi, Csordás, Gábor, Grass, Isabelle, Uhlirova, Mirka, Classen, Anne-Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389326/
https://www.ncbi.nlm.nih.gov/pubmed/30735120
http://dx.doi.org/10.7554/eLife.41036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389326/
https://www.ncbi.nlm.nih.gov/pubmed/30735120
http://dx.doi.org/10.7554/eLife.41036

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