Cargando…

rhIGF-1/rhIGFBP-3 in Preterm Infants: A Phase 2 Randomized Controlled Trial

OBJECTIVE: To investigate recombinant human insulin-like growth factor 1 complexed with its binding protein (rhIGF-1/rhIGFBP-3) for the prevention of retinopathy of prematurity (ROP) and other complications of prematurity among extremely preterm infants. STUDY DESIGN: This phase 2 trial was conducte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ley, David, Hallberg, Boubou, Hansen-Pupp, Ingrid, Dani, Carlo, Ramenghi, Luca A., Marlow, Neil, Beardsall, Kathryn, Bhatti, Faizah, Dunger, David, Higginson, Jason D., Mahaveer, Ajit, Mezu-Ndubuisi, Olachi J., Reynolds, Peter, Giannantonio, Carmen, van Weissenbruch, Mirjam, Barton, Norman, Tocoian, Adina, Hamdani, Mohamed, Jochim, Emily, Mangili, Alexandra, Chung, Jou-Ku, Turner, Mark A., Smith, Lois E. H., Hellström, Ann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389415/ https://www.ncbi.nlm.nih.gov/pubmed/30471715 http://dx.doi.org/10.1016/j.jpeds.2018.10.033

Ejemplares similares

Randomized Control Trial of Postnatal rhIGF-1/rhIGFBP-3 Replacement in Preterm Infants: Post-hoc Analysis of Its Effect on Brain Injury
por: Horsch, Sandra, et al.
Publicado: (2020)

Assessment of compatibility of rhIGF-1/rhIGFBP-3 with neonatal intravenous medications
por: Salamat-Miller, Nazila, et al.
Publicado: (2022)

Pilot dose-ranging of rhIGF-1/rhIGFBP-3 in a preterm lamb model of evolving bronchopulmonary dysplasia
por: Albertine, Kurt H., et al.
Publicado: (2023)

rhIGF-1 Therapy: A Silver Bullet for Bronchopulmonary Dysplasia Prevention?
por: Plosa, Erin J., et al.
Publicado: (2020)

Effectiveness and safety of rhIGF1 therapy in patients with or without Laron syndrome
por: Bang, Peter, et al.
Publicado: (2020)

Insulin‐like growth factor 1 has multisystem effects on foetal and preterm infant development
por: Hellström, Ann, et al.
Publicado: (2016)

In Vivo Angiography Quantifies Oxygen-Induced Retinopathy Vascular Recovery
por: Mezu-Ndubuisi, Olachi J.
Publicado: (2016)

Unmasking Systemic Racism and Unconscious Bias in Medical Workplaces: A Call to Servant Leadership
por: Mezu‐Ndubuisi, Olachi J.
Publicado: (2021)

Expression of Recombinant Human Insulin-like Growth Factor Type 1 (rhIGF-1) in Escherichia coli
por: Iranpoor, Hamidreza, et al.
Publicado: (2015)

rhIGF-1/BP3 Preserves Lung Growth and Prevents Pulmonary Hypertension in Experimental Bronchopulmonary Dysplasia
por: Seedorf, Gregory, et al.
Publicado: (2020)

The role of rhIGF-1/BP3 in the prevention of pulmonary hypertension in bronchopulmonary dysplasia and its underlying mechanism
por: Qu, Sehua, et al.
Publicado: (2023)

Subcutaneous administration of rhIGF-I post irradiation exposure enhances hematopoietic recovery and survival in BALB/c mice
por: Chen, Shilei, et al.
Publicado: (2012)

rhIGF-1 Therapy for Growth Failure and IGF-1 Deficiency in Congenital Disorder of Glycosylation Ia (PMM2 Deficiency)
por: Miller, Bradley S., et al.
Publicado: (2013)

The role of integrins in inflammation and angiogenesis
por: Mezu-Ndubuisi, Olachi J., et al.
Publicado: (2020)

Role of the Endothelium in Neonatal Diseases
por: Mezu-Ndubuisi, Olachi J, et al.
Publicado: (2022)

Inhibition of Human MCF-7 Breast Cancer Cells and HT-29 Colon Cancer Cells by Rice-Produced Recombinant Human Insulin-Like Growth Binding Protein-3 (rhIGFBP-3)
por: Cheung, Stanley C. K., et al.
Publicado: (2013)

Simultaneous Fluorescein Angiography and Spectral Domain Optical Coherence Tomography Correlate Retinal Thickness Changes to Vascular Abnormalities in an In Vivo Mouse Model of Retinopathy of Prematurity
por: Mezu-Ndubuisi, Olachi J., et al.
Publicado: (2017)

Community Preventive Health Education Intervention for Pediatric Iron-Deficiency Anemia in Rural Southeast Nigeria
por: Nwaba, Adaure, et al.
Publicado: (2022)

Longer Breastfeeding Associated with Childhood Anemia in Rural South-Eastern Nigeria
por: Buck, Sean, et al.
Publicado: (2019)

STUDIES ON BLOOD FACTORS Rh(A), Rh(B), AND Rh(C)
por: Unger, Lester J., et al.
Publicado: (1959)

Generating Fischer-Type Rh-Carbenes with Rh-Carbynoids
por: Palomo, Eric, et al.
Publicado: (2023)

History of Rh
por: Reid, M M
Publicado: (1997)

Occurrence of ABO And RhD Incompatibility with Rh Negative Mothers
por: Izetbegovic, Sebija
Publicado: (2013)

Retinopathy of prematurity shows alterations in Vegfa(164) isoform expression
por: Mezu-Ndubuisi, Olachi J., et al.
Publicado: (2021)

Latent toxoplasmosis and olfactory functions of Rh positive and Rh negative subjects
por: Flegr, Jaroslav, et al.
Publicado: (2018)

IGF-1 as a Drug for Preterm Infants: A Step-Wise Clinical Development
por: Hellström, Ann, et al.
Publicado: (2017)

Retinal vascular recovery revealed by retinal imaging following neonatal hypoxia ischemia in mice: Is there a role for tyrosine kinase receptor modulation?
por: Zafer, Dila, et al.
Publicado: (2022)

The Rh Problem in India
Publicado: (1946)

Gonadotropin-Releasing Hormone (GnRH) Receptor Structure and GnRH Binding
por: Flanagan, Colleen A., et al.
Publicado: (2017)

Heterogeneous Rh and Rh/Ag bimetallic nanoparticle catalysts immobilized on chiral polymers
por: Min, Hyemin, et al.
Publicado: (2019)

The role of GnRH metabolite, GnRH-(1-5), in endometrial cancer
por: Cho-Clark, Madelaine J., et al.
Publicado: (2023)

Melatonin Inhibits GnRH-1, GnRH-3 and GnRH Receptor Expression in the Brain of the European Sea Bass, Dicentrarchus labrax
por: Servili, Arianna, et al.
Publicado: (2013)

Comparison of GnRH Agonist, GnRH Antagonist, and GnRH Antagonist Mild Protocol of Controlled Ovarian Hyperstimulation in Good Prognosis Patients
por: Stimpfel, Martin, et al.
Publicado: (2015)

Preparation and Thermoelectric Characteristics of ITO/PtRh:PtRh Thin Film Thermocouple
por: Zhao, Xiaohui, et al.
Publicado: (2017)

RhCMV serostatus and vaccine adjuvant impact immunogenicity of RhCMV/SIV vaccines
por: Chang, W. L. William, et al.
Publicado: (2020)

A dinuclear Rh(−i)/Rh(i) complex bridged by biphilic phosphinine ligands
por: Masada, Koichiro, et al.
Publicado: (2023)

Gonadotropin-Releasing Hormone (GnRH)/GnRH Receptors and Their Role in the Treatment of Endometriosis
por: Resta, Christina, et al.
Publicado: (2023)

Long-term evaluation of retinal morphology and function in a mouse model of oxygen-induced retinopathy
por: Mezu-Ndubuisi, Olachi J., et al.
Publicado: (2020)

Anesthetic experience of a combined ABO- and Rh-incompatible living donor liver transplantation between an O Rh- recipient and a B Rh+ donor
por: Choi, Jaehyung, et al.
Publicado: (2013)

HEREDITY OF THE Rh BLOOD TYPES
por: Wiener, Alexander S., et al.
Publicado: (1944)

Cannot write session to /tmp/vufind_sessions/sess_lqmvp4h86lcijou7ef4af01vle