A child with Klinefelter syndrome and both IgE‐mediated food allergy and low proportion of naive Treg

This case suggests a possible association between Klinefelter Syndrome and decreased regulatory T cells (Treg) cells, relating to an increased risk of allergic and autoimmune disorders in these patients. The immune phenotyping of the circulating FOXP3+ naive Treg populations in KS patients may help...

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Autores principales: Frederick, Rachel, Vuillermin, Peter, Tang, Mimi L. K., Ponsonby, Anne‐Louise, Webster, Elise, Saffery, Richard, Collier, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389460/
https://www.ncbi.nlm.nih.gov/pubmed/30847194
http://dx.doi.org/10.1002/ccr3.1928
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author Frederick, Rachel
Vuillermin, Peter
Tang, Mimi L. K.
Ponsonby, Anne‐Louise
Webster, Elise
Saffery, Richard
Collier, Fiona
author_facet Frederick, Rachel
Vuillermin, Peter
Tang, Mimi L. K.
Ponsonby, Anne‐Louise
Webster, Elise
Saffery, Richard
Collier, Fiona
author_sort Frederick, Rachel
collection PubMed
description This case suggests a possible association between Klinefelter Syndrome and decreased regulatory T cells (Treg) cells, relating to an increased risk of allergic and autoimmune disorders in these patients. The immune phenotyping of the circulating FOXP3+ naive Treg populations in KS patients may help to indicate this predisposition.
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spelling pubmed-63894602019-03-07 A child with Klinefelter syndrome and both IgE‐mediated food allergy and low proportion of naive Treg Frederick, Rachel Vuillermin, Peter Tang, Mimi L. K. Ponsonby, Anne‐Louise Webster, Elise Saffery, Richard Collier, Fiona Clin Case Rep Case Reports This case suggests a possible association between Klinefelter Syndrome and decreased regulatory T cells (Treg) cells, relating to an increased risk of allergic and autoimmune disorders in these patients. The immune phenotyping of the circulating FOXP3+ naive Treg populations in KS patients may help to indicate this predisposition. John Wiley and Sons Inc. 2019-01-07 /pmc/articles/PMC6389460/ /pubmed/30847194 http://dx.doi.org/10.1002/ccr3.1928 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Frederick, Rachel
Vuillermin, Peter
Tang, Mimi L. K.
Ponsonby, Anne‐Louise
Webster, Elise
Saffery, Richard
Collier, Fiona
A child with Klinefelter syndrome and both IgE‐mediated food allergy and low proportion of naive Treg
title A child with Klinefelter syndrome and both IgE‐mediated food allergy and low proportion of naive Treg
title_full A child with Klinefelter syndrome and both IgE‐mediated food allergy and low proportion of naive Treg
title_fullStr A child with Klinefelter syndrome and both IgE‐mediated food allergy and low proportion of naive Treg
title_full_unstemmed A child with Klinefelter syndrome and both IgE‐mediated food allergy and low proportion of naive Treg
title_short A child with Klinefelter syndrome and both IgE‐mediated food allergy and low proportion of naive Treg
title_sort child with klinefelter syndrome and both ige‐mediated food allergy and low proportion of naive treg
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389460/
https://www.ncbi.nlm.nih.gov/pubmed/30847194
http://dx.doi.org/10.1002/ccr3.1928
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