Poorly differentiated cutaneous squamous cell carcinoma with osteoclast‐like giant cell: A rare, aggressive variant

Squamous Cell Carcinoma (SCC) with Osteoclast‐like giant cell (OLGC) is a rare SCC variant; only 10 cases have been reported. Our case suggests OLGC are resultant of a reactive process, driven by the fusion of adjacent macrophages. Knowledge regarding SCC with OLGC is of great importance as this ent...

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Detalles Bibliográficos
Autores principales: Venning, Victoria L., Myint, Esther, Pyne, John, Clark, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389463/
https://www.ncbi.nlm.nih.gov/pubmed/30847202
http://dx.doi.org/10.1002/ccr3.1955
Descripción
Sumario:Squamous Cell Carcinoma (SCC) with Osteoclast‐like giant cell (OLGC) is a rare SCC variant; only 10 cases have been reported. Our case suggests OLGC are resultant of a reactive process, driven by the fusion of adjacent macrophages. Knowledge regarding SCC with OLGC is of great importance as this entity has greater prometastatic potential compared to conventional SCC.

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