Poorly differentiated cutaneous squamous cell carcinoma with osteoclast‐like giant cell: A rare, aggressive variant

Squamous Cell Carcinoma (SCC) with Osteoclast‐like giant cell (OLGC) is a rare SCC variant; only 10 cases have been reported. Our case suggests OLGC are resultant of a reactive process, driven by the fusion of adjacent macrophages. Knowledge regarding SCC with OLGC is of great importance as this ent...

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Autores principales: Venning, Victoria L., Myint, Esther, Pyne, John, Clark, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389463/
https://www.ncbi.nlm.nih.gov/pubmed/30847202
http://dx.doi.org/10.1002/ccr3.1955
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author Venning, Victoria L.
Myint, Esther
Pyne, John
Clark, Simon
author_facet Venning, Victoria L.
Myint, Esther
Pyne, John
Clark, Simon
author_sort Venning, Victoria L.
collection PubMed
description Squamous Cell Carcinoma (SCC) with Osteoclast‐like giant cell (OLGC) is a rare SCC variant; only 10 cases have been reported. Our case suggests OLGC are resultant of a reactive process, driven by the fusion of adjacent macrophages. Knowledge regarding SCC with OLGC is of great importance as this entity has greater prometastatic potential compared to conventional SCC.
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spelling pubmed-63894632019-03-07 Poorly differentiated cutaneous squamous cell carcinoma with osteoclast‐like giant cell: A rare, aggressive variant Venning, Victoria L. Myint, Esther Pyne, John Clark, Simon Clin Case Rep Case Reports Squamous Cell Carcinoma (SCC) with Osteoclast‐like giant cell (OLGC) is a rare SCC variant; only 10 cases have been reported. Our case suggests OLGC are resultant of a reactive process, driven by the fusion of adjacent macrophages. Knowledge regarding SCC with OLGC is of great importance as this entity has greater prometastatic potential compared to conventional SCC. John Wiley and Sons Inc. 2019-01-09 /pmc/articles/PMC6389463/ /pubmed/30847202 http://dx.doi.org/10.1002/ccr3.1955 Text en © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Venning, Victoria L.
Myint, Esther
Pyne, John
Clark, Simon
Poorly differentiated cutaneous squamous cell carcinoma with osteoclast‐like giant cell: A rare, aggressive variant
title Poorly differentiated cutaneous squamous cell carcinoma with osteoclast‐like giant cell: A rare, aggressive variant
title_full Poorly differentiated cutaneous squamous cell carcinoma with osteoclast‐like giant cell: A rare, aggressive variant
title_fullStr Poorly differentiated cutaneous squamous cell carcinoma with osteoclast‐like giant cell: A rare, aggressive variant
title_full_unstemmed Poorly differentiated cutaneous squamous cell carcinoma with osteoclast‐like giant cell: A rare, aggressive variant
title_short Poorly differentiated cutaneous squamous cell carcinoma with osteoclast‐like giant cell: A rare, aggressive variant
title_sort poorly differentiated cutaneous squamous cell carcinoma with osteoclast‐like giant cell: a rare, aggressive variant
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389463/
https://www.ncbi.nlm.nih.gov/pubmed/30847202
http://dx.doi.org/10.1002/ccr3.1955
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