Acute promyelocytic leukemia presenting as recurrent spinal myeloid sarcomas 3 years before developing leukemia: A case report with review of literature

The de novo myeloid sarcoma (MS) type of acute promyelocytic leukemia (APL) is rare, and clinical features may differ from extramedullary diseases in advanced APL. Many cases occur as a spinal tumor, and some occur in the absence of bone‐marrow diseases or coagulation abnormalities. Fluorescence in...

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Detalles Bibliográficos
Autores principales: Yamashita, Tomoko, Nishijima, Akihiko, Noguchi, Yuma, Narukawa, Kensuke, Oshikawa, Gaku, Takano, Hina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389481/
https://www.ncbi.nlm.nih.gov/pubmed/30847197
http://dx.doi.org/10.1002/ccr3.1991
Descripción
Sumario:The de novo myeloid sarcoma (MS) type of acute promyelocytic leukemia (APL) is rare, and clinical features may differ from extramedullary diseases in advanced APL. Many cases occur as a spinal tumor, and some occur in the absence of bone‐marrow diseases or coagulation abnormalities. Fluorescence in situ hybridization analysis of MS tissue is useful for accurate diagnosis, even in preserved tissue.

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