Mice harboring an MCTO mutation exhibit renal failure resembling nephropathy in human patients

Multicentric carpotarsal osteolysis (MCTO) is a condition involving progressive osteolysis of the carpal and tarsal bones that is associated with glomerular sclerosis and renal failure (MCTO nephropathy). Previous work identified an autosomal dominant missense mutation in the transactivation domain...

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Detalles Bibliográficos
Autores principales: Tsunakawa, Yuki, Hamada, Michito, Matsunaga, Yurina, Fuseya, Sayaka, Jeon, Hyojung, Wakimoto, Yuji, Usui, Toshiaki, Kanai, Maho, Mizuno, Seiya, Morito, Naoki, Takahashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2018
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389512/
https://www.ncbi.nlm.nih.gov/pubmed/30369533
http://dx.doi.org/10.1538/expanim.18-0093

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