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Negative lusitropic property of nifekalant identified using ventricular pressure-volume loop analyses in anesthetized monkeys

The present study was conducted to clarify multiple cardiohemodynamic and electrophysiological properties including inotropic/lusitropic effects of nifekalant, a class III antiarrhythmic drug, in an isoflurane-anesthetized monkey. Nifekalant was administered intravenously at the therapeutic dose of...

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Detalles Bibliográficos
Autores principales: Ishizaka, Tomomichi, Yoshimatsu, Yu, Maeda, Yu, Chiba, Katsuyoshi, Mori, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389513/
https://www.ncbi.nlm.nih.gov/pubmed/30333366
http://dx.doi.org/10.1538/expanim.18-0098

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