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Negative lusitropic property of nifekalant identified using ventricular pressure-volume loop analyses in anesthetized monkeys
The present study was conducted to clarify multiple cardiohemodynamic and electrophysiological properties including inotropic/lusitropic effects of nifekalant, a class III antiarrhythmic drug, in an isoflurane-anesthetized monkey. Nifekalant was administered intravenously at the therapeutic dose of...
Autores principales: | Ishizaka, Tomomichi, Yoshimatsu, Yu, Maeda, Yu, Chiba, Katsuyoshi, Mori, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Association for Laboratory Animal Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389513/ https://www.ncbi.nlm.nih.gov/pubmed/30333366 http://dx.doi.org/10.1538/expanim.18-0098 |
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