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Glomerular membrane attack complex is not a reliable marker of ongoing C5 activation in lupus nephritis
Complement plays an important role in the pathogenesis of lupus nephritis (LN). With the emergence of therapeutic complement inhibition, there is a need to identify patients in whom complement-driven inflammation is a major cause of kidney injury in LN. Clinical and histopathological data were obtai...
Autores principales: | Wilson, Hannah R., Medjeral-Thomas, Nicholas R., Gilmore, Alyssa C., Trivedi, Pritesh, Seyb, Kathleen, Farzaneh-Far, Ramin, Gunnarsson, Iva, Zickert, Agneta, Cairns, Thomas D., Lightstone, Liz, Cook, H. Terence, Pickering, Matthew C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389546/ https://www.ncbi.nlm.nih.gov/pubmed/30655025 http://dx.doi.org/10.1016/j.kint.2018.09.027 |
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