Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation

Foxp3(+) regulatory T (Treg) cells restrict immune pathology in inflamed tissues; however, an inflammatory environment presents a threat to Treg cell identity and function. Here, we establish a transcriptional signature of central nervous system (CNS) Treg cells that accumulate during experimental a...

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Detalles Bibliográficos
Autores principales: Garg, Garima, Muschaweckh, Andreas, Moreno, Helena, Vasanthakumar, Ajithkumar, Floess, Stefan, Lepennetier, Gildas, Oellinger, Rupert, Zhan, Yifan, Regen, Tommy, Hiltensperger, Michael, Peter, Christian, Aly, Lilian, Knier, Benjamin, Palam, Lakshmi Reddy, Kapur, Reuben, Kaplan, Mark H., Waisman, Ari, Rad, Roland, Schotta, Gunnar, Huehn, Jochen, Kallies, Axel, Korn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389594/
https://www.ncbi.nlm.nih.gov/pubmed/30759395
http://dx.doi.org/10.1016/j.celrep.2019.01.070

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