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Inflammatory hepatocellular adenoma in a patient with Turner’s syndrome: A case report
INTRODUCTION: Hepatocellular adenoma (HCA) is a rare benign tumor and is related to the use of an oral contraceptive pill. Turner’s syndrome requires various hormone replacement therapies, including the pill which is used as a female hormone replacement therapy. Herein we report a case of Turner’s s...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389595/ https://www.ncbi.nlm.nih.gov/pubmed/30798096 http://dx.doi.org/10.1016/j.ijscr.2019.02.017 |
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author | Nemoto, Satoshi Ariizumi, Shun-ichi Kotera, Yoshihito Omori, Akiko Yamashita, Shingo Kato, Taka-aki Aoyama, Shota Egawa, Hiroto Yamamoto, Masakazu |
author_facet | Nemoto, Satoshi Ariizumi, Shun-ichi Kotera, Yoshihito Omori, Akiko Yamashita, Shingo Kato, Taka-aki Aoyama, Shota Egawa, Hiroto Yamamoto, Masakazu |
author_sort | Nemoto, Satoshi |
collection | PubMed |
description | INTRODUCTION: Hepatocellular adenoma (HCA) is a rare benign tumor and is related to the use of an oral contraceptive pill. Turner’s syndrome requires various hormone replacement therapies, including the pill which is used as a female hormone replacement therapy. Herein we report a case of Turner’s syndrome with HCA treated by liver segmentectomy. PRESENTATION OF CASE: A 36-year-old woman with Turner’s syndrome was treated with oral contraceptive pills as a female hormone replacement therapy for 20 years. She presented with fatigue and liver tumor. Liver tumors in the posterior lobe measuring 60 mm and 10 mm in diameter were detected on CT; hence, she was referred to our department. Both the tumors showed high intensity in the arterial phase, iso-intensity in the portal and late phases, and low intensity in the hepatobiliary phase on Gb-EOB-MRI. She was diagnosed with multiple HCAs and underwent segmentectomy Section 7. Pathologically, both the tumors were diagnosed as HCAs, and inflammatory markers were detected by immunohistochemistry. Thirteen months postoperatively, she was doing well and there was no evidence of recurrence of HCA without the pill. DISCUSSION: There is only one report of HCA in patients with TS (Espat et al., 2000). We reported a case of multiple HCAs in a patient with TS underwent hepatectomy. CONCLUSION: With the use of the contraceptive pill as a long-term female hormone replacement therapy for Turner’s syndrome, careful attention is required for HCA. |
format | Online Article Text |
id | pubmed-6389595 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-63895952019-03-07 Inflammatory hepatocellular adenoma in a patient with Turner’s syndrome: A case report Nemoto, Satoshi Ariizumi, Shun-ichi Kotera, Yoshihito Omori, Akiko Yamashita, Shingo Kato, Taka-aki Aoyama, Shota Egawa, Hiroto Yamamoto, Masakazu Int J Surg Case Rep Article INTRODUCTION: Hepatocellular adenoma (HCA) is a rare benign tumor and is related to the use of an oral contraceptive pill. Turner’s syndrome requires various hormone replacement therapies, including the pill which is used as a female hormone replacement therapy. Herein we report a case of Turner’s syndrome with HCA treated by liver segmentectomy. PRESENTATION OF CASE: A 36-year-old woman with Turner’s syndrome was treated with oral contraceptive pills as a female hormone replacement therapy for 20 years. She presented with fatigue and liver tumor. Liver tumors in the posterior lobe measuring 60 mm and 10 mm in diameter were detected on CT; hence, she was referred to our department. Both the tumors showed high intensity in the arterial phase, iso-intensity in the portal and late phases, and low intensity in the hepatobiliary phase on Gb-EOB-MRI. She was diagnosed with multiple HCAs and underwent segmentectomy Section 7. Pathologically, both the tumors were diagnosed as HCAs, and inflammatory markers were detected by immunohistochemistry. Thirteen months postoperatively, she was doing well and there was no evidence of recurrence of HCA without the pill. DISCUSSION: There is only one report of HCA in patients with TS (Espat et al., 2000). We reported a case of multiple HCAs in a patient with TS underwent hepatectomy. CONCLUSION: With the use of the contraceptive pill as a long-term female hormone replacement therapy for Turner’s syndrome, careful attention is required for HCA. Elsevier 2019-02-15 /pmc/articles/PMC6389595/ /pubmed/30798096 http://dx.doi.org/10.1016/j.ijscr.2019.02.017 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Nemoto, Satoshi Ariizumi, Shun-ichi Kotera, Yoshihito Omori, Akiko Yamashita, Shingo Kato, Taka-aki Aoyama, Shota Egawa, Hiroto Yamamoto, Masakazu Inflammatory hepatocellular adenoma in a patient with Turner’s syndrome: A case report |
title | Inflammatory hepatocellular adenoma in a patient with Turner’s syndrome: A case report |
title_full | Inflammatory hepatocellular adenoma in a patient with Turner’s syndrome: A case report |
title_fullStr | Inflammatory hepatocellular adenoma in a patient with Turner’s syndrome: A case report |
title_full_unstemmed | Inflammatory hepatocellular adenoma in a patient with Turner’s syndrome: A case report |
title_short | Inflammatory hepatocellular adenoma in a patient with Turner’s syndrome: A case report |
title_sort | inflammatory hepatocellular adenoma in a patient with turner’s syndrome: a case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389595/ https://www.ncbi.nlm.nih.gov/pubmed/30798096 http://dx.doi.org/10.1016/j.ijscr.2019.02.017 |
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