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Cardiac Specific Knockout of p53 Decreases ER Stress-Induced Mitochondrial Damage

Endoplasmic reticulum (ER) stress contributes to cardiovascular disease including heart failure. Interactions between the ER and mitochondria during ER stress can impair the mitochondrial respiratory chain and increase cell injury. p53 is a tumor suppressor protein that regulates apoptosis. p53 cont...

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Detalles Bibliográficos
Autores principales:	Chen, Qun, Thompson, Jeremy, Hu, Ying, Das, Anindita, Lesnefsky, Edward J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389610/ https://www.ncbi.nlm.nih.gov/pubmed/30838215 http://dx.doi.org/10.3389/fcvm.2019.00010

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