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From Desert to Medicine: A Review of Camel Genomics and Therapeutic Products

Camels have an important role in the lives of human beings, especially in arid regions, due to their multipurpose role and unique ability to adapt to harsh conditions. In spite of its enormous economic, cultural, and biological importance, the camel genome has not been widely studied. The size of ca...

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Detalles Bibliográficos
Autores principales: Ali, Amanat, Baby, Bincy, Vijayan, Ranjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389616/
https://www.ncbi.nlm.nih.gov/pubmed/30838017
http://dx.doi.org/10.3389/fgene.2019.00017
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author Ali, Amanat
Baby, Bincy
Vijayan, Ranjit
author_facet Ali, Amanat
Baby, Bincy
Vijayan, Ranjit
author_sort Ali, Amanat
collection PubMed
description Camels have an important role in the lives of human beings, especially in arid regions, due to their multipurpose role and unique ability to adapt to harsh conditions. In spite of its enormous economic, cultural, and biological importance, the camel genome has not been widely studied. The size of camel genome is roughly 2.38 GB, containing over 20,000 genes. The unusual genetic makeup of the camel is the main reason behind its ability to survive under extreme environmental conditions. The camel genome harbors several unique variations which are being investigated for the treatment of several disorders. Various natural products from camels have also been tested and prescribed as adjunct therapy to control the progression of ailments. Interestingly, the camel employs unique immunological and molecular mechanisms against pathogenic agents and pathological conditions. Here, we broadly review camel classification, distribution and breed as well as recent progress in the determination of the camel genome, its size, genetic distribution, response to various physiological conditions, immunogenetics and the medicinal potential of camel gene products.
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spelling pubmed-63896162019-03-05 From Desert to Medicine: A Review of Camel Genomics and Therapeutic Products Ali, Amanat Baby, Bincy Vijayan, Ranjit Front Genet Genetics Camels have an important role in the lives of human beings, especially in arid regions, due to their multipurpose role and unique ability to adapt to harsh conditions. In spite of its enormous economic, cultural, and biological importance, the camel genome has not been widely studied. The size of camel genome is roughly 2.38 GB, containing over 20,000 genes. The unusual genetic makeup of the camel is the main reason behind its ability to survive under extreme environmental conditions. The camel genome harbors several unique variations which are being investigated for the treatment of several disorders. Various natural products from camels have also been tested and prescribed as adjunct therapy to control the progression of ailments. Interestingly, the camel employs unique immunological and molecular mechanisms against pathogenic agents and pathological conditions. Here, we broadly review camel classification, distribution and breed as well as recent progress in the determination of the camel genome, its size, genetic distribution, response to various physiological conditions, immunogenetics and the medicinal potential of camel gene products. Frontiers Media S.A. 2019-02-19 /pmc/articles/PMC6389616/ /pubmed/30838017 http://dx.doi.org/10.3389/fgene.2019.00017 Text en Copyright © 2019 Ali, Baby and Vijayan. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Ali, Amanat
Baby, Bincy
Vijayan, Ranjit
From Desert to Medicine: A Review of Camel Genomics and Therapeutic Products
title From Desert to Medicine: A Review of Camel Genomics and Therapeutic Products
title_full From Desert to Medicine: A Review of Camel Genomics and Therapeutic Products
title_fullStr From Desert to Medicine: A Review of Camel Genomics and Therapeutic Products
title_full_unstemmed From Desert to Medicine: A Review of Camel Genomics and Therapeutic Products
title_short From Desert to Medicine: A Review of Camel Genomics and Therapeutic Products
title_sort from desert to medicine: a review of camel genomics and therapeutic products
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389616/
https://www.ncbi.nlm.nih.gov/pubmed/30838017
http://dx.doi.org/10.3389/fgene.2019.00017
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