Cargando…
Developmental Comparison of Ceramide in Wild-Type and Cln3(Δex7/8) Mouse Brains and Sera
CLN3 disease is a neurodevelopmental disease leading to early visual failure, motor decline, and death. CLN3 pathogenesis has been linked to dysregulation of ceramide, a key intracellular messenger impacting various biological functions. Ceramide is upregulated in brains of CLN3 patients and activat...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389635/ https://www.ncbi.nlm.nih.gov/pubmed/30837943 http://dx.doi.org/10.3389/fneur.2019.00128 |