Recent Advances on the Molecular Mechanism of Cervical Carcinogenesis Based on Systems Biology Technologies

Cervical cancer is one of the common malignancies in women worldwide. Exploration of pathogenesis and molecular mechanism of cervical cancer is pivotal for development of effective treatment for this disease. Recently, systems biology approaches based on high-throughput technologies have been carrie...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Min, Ye, Miaomiao, Zhou, Junhan, Wang, Z. Peter, Zhu, Xueqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389684/
https://www.ncbi.nlm.nih.gov/pubmed/30847042
http://dx.doi.org/10.1016/j.csbj.2019.02.001
_version_ 1783397980203646976
author Lin, Min
Ye, Miaomiao
Zhou, Junhan
Wang, Z. Peter
Zhu, Xueqiong
author_facet Lin, Min
Ye, Miaomiao
Zhou, Junhan
Wang, Z. Peter
Zhu, Xueqiong
author_sort Lin, Min
collection PubMed
description Cervical cancer is one of the common malignancies in women worldwide. Exploration of pathogenesis and molecular mechanism of cervical cancer is pivotal for development of effective treatment for this disease. Recently, systems biology approaches based on high-throughput technologies have been carried out to investigate the expression of some genes and proteins in genomics, transcriptomics, proteomics, and metabonomics of cervical cancer. Compared with traditional methods，systems biology technology has been shown to provide large of information regarding prognostic biomarkers and therapeutic targets for cervical cancer. These molecular signatures from system biology technology could be useful to understand the molecular mechanisms of cervical cancer development and progression, and help physicians to design targeted therapeutic strategies for patients with cervical cancer.
format Online
Article
Text
id pubmed-6389684
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Research Network of Computational and Structural Biotechnology
record_format MEDLINE/PubMed
spelling pubmed-63896842019-03-07 Recent Advances on the Molecular Mechanism of Cervical Carcinogenesis Based on Systems Biology Technologies Lin, Min Ye, Miaomiao Zhou, Junhan Wang, Z. Peter Zhu, Xueqiong Comput Struct Biotechnol J Review Article Cervical cancer is one of the common malignancies in women worldwide. Exploration of pathogenesis and molecular mechanism of cervical cancer is pivotal for development of effective treatment for this disease. Recently, systems biology approaches based on high-throughput technologies have been carried out to investigate the expression of some genes and proteins in genomics, transcriptomics, proteomics, and metabonomics of cervical cancer. Compared with traditional methods，systems biology technology has been shown to provide large of information regarding prognostic biomarkers and therapeutic targets for cervical cancer. These molecular signatures from system biology technology could be useful to understand the molecular mechanisms of cervical cancer development and progression, and help physicians to design targeted therapeutic strategies for patients with cervical cancer. Research Network of Computational and Structural Biotechnology 2019-02-07 /pmc/articles/PMC6389684/ /pubmed/30847042 http://dx.doi.org/10.1016/j.csbj.2019.02.001 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Lin, Min
Ye, Miaomiao
Zhou, Junhan
Wang, Z. Peter
Zhu, Xueqiong
Recent Advances on the Molecular Mechanism of Cervical Carcinogenesis Based on Systems Biology Technologies
title Recent Advances on the Molecular Mechanism of Cervical Carcinogenesis Based on Systems Biology Technologies
title_full Recent Advances on the Molecular Mechanism of Cervical Carcinogenesis Based on Systems Biology Technologies
title_fullStr Recent Advances on the Molecular Mechanism of Cervical Carcinogenesis Based on Systems Biology Technologies
title_full_unstemmed Recent Advances on the Molecular Mechanism of Cervical Carcinogenesis Based on Systems Biology Technologies
title_short Recent Advances on the Molecular Mechanism of Cervical Carcinogenesis Based on Systems Biology Technologies
title_sort recent advances on the molecular mechanism of cervical carcinogenesis based on systems biology technologies
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389684/
https://www.ncbi.nlm.nih.gov/pubmed/30847042
http://dx.doi.org/10.1016/j.csbj.2019.02.001
work_keys_str_mv AT linmin recentadvancesonthemolecularmechanismofcervicalcarcinogenesisbasedonsystemsbiologytechnologies
AT yemiaomiao recentadvancesonthemolecularmechanismofcervicalcarcinogenesisbasedonsystemsbiologytechnologies
AT zhoujunhan recentadvancesonthemolecularmechanismofcervicalcarcinogenesisbasedonsystemsbiologytechnologies
AT wangzpeter recentadvancesonthemolecularmechanismofcervicalcarcinogenesisbasedonsystemsbiologytechnologies
AT zhuxueqiong recentadvancesonthemolecularmechanismofcervicalcarcinogenesisbasedonsystemsbiologytechnologies

Ejemplares similares