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Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium

Endothelial dysfunction underlies the pathobiology of cerebrovascular disease. Mast cells are located in close proximity to the vasculature, and vasoactive mediators released upon their activation can promote endothelial activation leading to blood brain barrier (BBB) dysfunction. We examined the me...

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Detalles Bibliográficos
Autores principales: Tran, Huy, Mittal, Aditya, Sagi, Varun, Luk, Kathryn, Nguyen, Aithanh, Gupta, Mihir, Nguyen, Julia, Lamarre, Yann, Lei, Jianxun, Guedes, Alonso, Gupta, Kalpna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389721/
https://www.ncbi.nlm.nih.gov/pubmed/30837844
http://dx.doi.org/10.3389/fncel.2019.00056