Cargando…
Drug repositioning in epilepsy reveals novel antiseizure candidates
OBJECTIVE: Epilepsy treatment falls short in ~30% of cases. A better understanding of epilepsy pathophysiology can guide rational drug development in this difficult to treat condition. We tested a low‐cost, drug‐repositioning strategy to identify candidate epilepsy drugs that are already FDA‐approve...
Autores principales: | Brueggeman, Leo, Sturgeon, Morgan L., Martin, Russell M., Grossbach, Andrew J., Nagahama, Yasunori, Zhang, Angela, Howard, Mathew A., Kawasaki, Hiroto, Wu, Shu, Cornell, Robert A., Michaelson, Jacob J., Bassuk, Alexander G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389756/ https://www.ncbi.nlm.nih.gov/pubmed/30847362 http://dx.doi.org/10.1002/acn3.703 |
Ejemplares similares
-
The opioid antagonist naltrexone decreases seizure‐like activity in genetic and chemically induced epilepsy models
por: Sturgeon, Morgan L., et al.
Publicado: (2021) -
Author Correction: Forecasting risk gene discovery in autism with machine learning and genome-scale data
por: Brueggeman, Leo, et al.
Publicado: (2020) -
Forecasting risk gene discovery in autism with machine learning and genome-scale data
por: Brueggeman, Leo, et al.
Publicado: (2020) -
Response to subsequent antiseizure medications after first antiseizure medication failure in newly diagnosed epilepsy
por: Hersi, Hire, et al.
Publicado: (2022) -
Epilepsy, Antiseizure Therapy, and Sleep Cycle Parameters
por: Shvarts, Vladimir, et al.
Publicado: (2013)