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Three Years' Experience of a Novel Biosynthetic Cellulose Dressing in Burns

Objective: The use of porcine xenograft (PX) is widely spread in burn care. However, it may cause immunologic responses and other ethical and cultural considerations in different cultures. Therefore, there is a need for alternatives. The aim of this work is to test a novel biosynthetic cellulose dre...

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Autores principales: Karlsson, Matilda, Olofsson, Pia, Steinvall, Ingrid, Sjöberg, Folke, Thorfinn, Johan, Elmasry, Moustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389762/
https://www.ncbi.nlm.nih.gov/pubmed/30809423
http://dx.doi.org/10.1089/wound.2018.0790
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author Karlsson, Matilda
Olofsson, Pia
Steinvall, Ingrid
Sjöberg, Folke
Thorfinn, Johan
Elmasry, Moustafa
author_facet Karlsson, Matilda
Olofsson, Pia
Steinvall, Ingrid
Sjöberg, Folke
Thorfinn, Johan
Elmasry, Moustafa
author_sort Karlsson, Matilda
collection PubMed
description Objective: The use of porcine xenograft (PX) is widely spread in burn care. However, it may cause immunologic responses and other ethical and cultural considerations in different cultures. Therefore, there is a need for alternatives. The aim of this work is to test a novel biosynthetic cellulose dressing (Epiprotect(®)) on burn patients. Approach: Charts from 38 patients with superficial burns (SBs) (n = 18) or excised burns (n = 20) that got biosynthetic cellulose dressing instead of PX at a national burn center during 3 years were reviewed. Time to healing, length of stay, and wound infection were extracted from the medical records. Results: SBs hospitalization time was 11 days comparable to PXs reported by others. In the excised group, median duration of hospital stay was 35 days. Time to healing was 28 days. Seven wound infections were confirmed in the superficial group (39%) and 11 infections in the excised group (61%). Patients with superficial wounds reported pain relief on application. Innovation: A dressing (17 × 21 cm) consisting of biosynthetic cellulose replacing PX. Conclusion: Outcome of treatment of SBs or temporary coverage of excised deep burns with biosynthetic cellulose is comparable to treatment with PX. However, biosynthetic cellulose has benefits such as providing pain relief on application and ethical or cultural issues with the material is nonexistent.
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spelling pubmed-63897622019-02-26 Three Years' Experience of a Novel Biosynthetic Cellulose Dressing in Burns Karlsson, Matilda Olofsson, Pia Steinvall, Ingrid Sjöberg, Folke Thorfinn, Johan Elmasry, Moustafa Adv Wound Care (New Rochelle) Technology Advances Objective: The use of porcine xenograft (PX) is widely spread in burn care. However, it may cause immunologic responses and other ethical and cultural considerations in different cultures. Therefore, there is a need for alternatives. The aim of this work is to test a novel biosynthetic cellulose dressing (Epiprotect(®)) on burn patients. Approach: Charts from 38 patients with superficial burns (SBs) (n = 18) or excised burns (n = 20) that got biosynthetic cellulose dressing instead of PX at a national burn center during 3 years were reviewed. Time to healing, length of stay, and wound infection were extracted from the medical records. Results: SBs hospitalization time was 11 days comparable to PXs reported by others. In the excised group, median duration of hospital stay was 35 days. Time to healing was 28 days. Seven wound infections were confirmed in the superficial group (39%) and 11 infections in the excised group (61%). Patients with superficial wounds reported pain relief on application. Innovation: A dressing (17 × 21 cm) consisting of biosynthetic cellulose replacing PX. Conclusion: Outcome of treatment of SBs or temporary coverage of excised deep burns with biosynthetic cellulose is comparable to treatment with PX. However, biosynthetic cellulose has benefits such as providing pain relief on application and ethical or cultural issues with the material is nonexistent. Mary Ann Liebert, Inc., publishers 2019-02-01 2019-02-13 /pmc/articles/PMC6389762/ /pubmed/30809423 http://dx.doi.org/10.1089/wound.2018.0790 Text en © Matilda Karlsson et al. 2018; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technology Advances
Karlsson, Matilda
Olofsson, Pia
Steinvall, Ingrid
Sjöberg, Folke
Thorfinn, Johan
Elmasry, Moustafa
Three Years' Experience of a Novel Biosynthetic Cellulose Dressing in Burns
title Three Years' Experience of a Novel Biosynthetic Cellulose Dressing in Burns
title_full Three Years' Experience of a Novel Biosynthetic Cellulose Dressing in Burns
title_fullStr Three Years' Experience of a Novel Biosynthetic Cellulose Dressing in Burns
title_full_unstemmed Three Years' Experience of a Novel Biosynthetic Cellulose Dressing in Burns
title_short Three Years' Experience of a Novel Biosynthetic Cellulose Dressing in Burns
title_sort three years' experience of a novel biosynthetic cellulose dressing in burns
topic Technology Advances
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389762/
https://www.ncbi.nlm.nih.gov/pubmed/30809423
http://dx.doi.org/10.1089/wound.2018.0790
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