Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism

The antimicrobial peptide cathelicidin inhibits development of colitis-associated colon cancer. However, the role of cathelicidin in colon cancer metastasis remains unknown. We hypothesized that cathelicidin is effective in inhibiting colon cancer metastasis. Human colon cancer HT-29 cells were inje...

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Detalles Bibliográficos
Autores principales: Wang, Jiani, Cheng, Michelle, Law, Ivy K.M., Ortiz, Christina, Sun, Mingjun, Koon, Hon Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389776/
https://www.ncbi.nlm.nih.gov/pubmed/30847383
http://dx.doi.org/10.1016/j.omto.2019.01.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389776/
https://www.ncbi.nlm.nih.gov/pubmed/30847383
http://dx.doi.org/10.1016/j.omto.2019.01.004

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