Cargando…

Nitidine Chloride Inhibits SIN1 Expression in Osteosarcoma Cells

Nitidine chloride (NC) has been demonstrated to exert a tumor-suppressive function in various types of human cancers. However, the detailed mechanism of NC-mediated anti-tumor effects remains elusive. It has been reported that SIN1, a component of mTORC2 (mammalian target of rapamycin complex C2), p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Hui, Cao, Tong, Zhang, Xiaoqing, Shi, Ying, Zhang, Qing, Chai, Shuo, Yu, Li, Jin, Guoxi, Ma, Jia, Wang, Peter, Li, Yuyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389778/ https://www.ncbi.nlm.nih.gov/pubmed/30847386 http://dx.doi.org/10.1016/j.omto.2019.01.005

Ejemplares similares

Nitidine chloride suppresses NEDD4 expression in lung cancer cells
por: Zhang, Jing, et al.
Publicado: (2020)

Nitidine chloride possesses anticancer property in lung cancer cells through activating Hippo signaling pathway
por: Zhang, Jing, et al.
Publicado: (2020)

Antitumor functions and mechanisms of nitidine chloride in human cancers
por: Cui, Yue, et al.
Publicado: (2020)

Insights into an NEk2 inhibitory profile of nitidine chloride by molecular docking and biological evaluation
por: Li, Danni, et al.
Publicado: (2022)

Nitidine chloride inhibits hepatic cancer growth via modulation of multiple signaling pathways
por: Lin, Jiumao, et al.
Publicado: (2014)

Nitidine chloride induces cardiac hypertrophy in mice by targeting autophagy-related 4B cysteine peptidase
por: Hong, Yang, et al.
Publicado: (2022)

Nitidine chloride inhibits proliferation and induces apoptosis in colorectal cancer cells by suppressing the ERK signaling pathway
por: ZHAI, HUIYUAN, et al.
Publicado: (2016)

The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma
por: Gao, Li, et al.
Publicado: (2022)

Nitidine Chloride Alleviates Inflammation and Cellular Senescence in Murine Osteoarthritis Through Scavenging ROS
por: Lin, Changjian, et al.
Publicado: (2022)

Nitidine Chloride Triggers Autophagy and Apoptosis of Ovarian Cancer Cells through Akt/mTOR Signaling Pathway
por: Lian, Chaoqun, et al.
Publicado: (2023)

Hedgehog pathway is involved in nitidine chloride induced inhibition of epithelial-mesenchymal transition and cancer stem cells-like properties in breast cancer cells
por: Sun, Mingjuan, et al.
Publicado: (2016)

Nitidine chloride inhibits the appearance of cancer stem-like properties and regulates potential the mitochondrial membrane alterations of colon cancer cells
por: Gong, Hongyan, et al.
Publicado: (2020)

A novel nitidine chloride nanoparticle overcomes the stemness of CD133(+)EPCAM(+) Huh7 hepatocellular carcinoma cells for liver cancer therapy
por: Li, Danni, et al.
Publicado: (2022)

Gene profiling of HepG2 cells following nitidine chloride treatment: An investigation with microarray and Connectivity Mapping
por: Liu, Li-Min, et al.
Publicado: (2019)

DNA topoisomerase 1 and 2A function as oncogenes in liver cancer and may be direct targets of nitidine chloride
por: Liu, Li-Min, et al.
Publicado: (2018)

Nitidine chloride suppresses epithelial‐mesenchymal transition and stem cell‐like properties in glioblastoma by regulating JAK2/STAT3 signaling
por: Jia, Mingbo, et al.
Publicado: (2021)

Novel Agent Nitidine Chloride Induces Erythroid Differentiation and Apoptosis in CML Cells through c-Myc-miRNAs Axis
por: Liu, Na, et al.
Publicado: (2015)

Nitidine Chloride Is a Potential Alternative Therapy for Glioma Through Inducing Endoplasmic Reticulum Stress and Alleviating Epithelial-Mesenchymal Transition
por: Chen, Zihang, et al.
Publicado: (2020)

Folic acid modified TPGS as a novel nano-micelle for delivery of nitidine chloride to improve apoptosis induction in Huh7 human hepatocellular carcinoma
por: Li, Danni, et al.
Publicado: (2021)

Nitidine chloride prevents OVX-induced bone loss via suppressing NFATc1-mediated osteoclast differentiation
por: Liu, Qian, et al.
Publicado: (2016)

High throughput circRNA sequencing analysis reveals novel insights into the mechanism of nitidine chloride against hepatocellular carcinoma
por: Xiong, Dan-dan, et al.
Publicado: (2019)

Nitidine chloride acts as an apoptosis inducer in human oral cancer cells and a nude mouse xenograft model via inhibition of STAT3
por: Kim, Lee-Han, et al.
Publicado: (2017)

Structurally Simple Phenanthridine Analogues Based on Nitidine and Their Antitumor Activities
por: Qin, Shu-Qin, et al.
Publicado: (2019)

A new insight into the apoptotic effect of nitidine chloride targeting Checkpoint kinase 2 in human cervical cancer in vitro
por: Kwon, Hye-Jeong, et al.
Publicado: (2019)

Nitidine chloride, a benzophenanthridine alkaloid from Zanthoxylum nitidum (Roxb.) DC., exerts multiple beneficial properties, especially in tumors and inflammation-related diseases
por: Lu, Qiang, et al.
Publicado: (2022)

Nitidine chloride induces caspase 3/GSDME-dependent pyroptosis by inhibting PI3K/Akt pathway in lung cancer
por: Yu, Fei, et al.
Publicado: (2022)

Biological activities of nitidine, a potential anti-malarial lead compound
por: Bouquet, Jérome, et al.
Publicado: (2012)

Tumor-Selective Cytotoxicity of Nitidine Results from Its Rapid Accumulation into Mitochondria
por: Iwasaki, Hironori, et al.
Publicado: (2017)

Inhibition of Macropinocytosis Enhances the Sensitivity of Osteosarcoma Cells to Benzethonium Chloride
por: Xia, Haichao, et al.
Publicado: (2023)

Multiple shoot regeneration and effect of sugars on growth and nitidine accumulation in shoot cultures of Toddalia asiatica
por: Praveena, Chinthala, et al.
Publicado: (2014)

Cobalt chloride inhibits tumor formation in osteosarcoma cells through upregulation of HIF-1α
por: ZHANG, BO, et al.
Publicado: (2013)

Volume-sensitive chloride channels are involved in cisplatin treatment of osteosarcoma
por: CAI, SIYI, et al.
Publicado: (2015)

Prazosin inhibits the growth and mobility of osteosarcoma cells
por: An, Ming, et al.
Publicado: (2019)

BMP4 overexpression induces the upregulation of APP/Tau and memory deficits in Alzheimer’s disease
por: Zhang, Xiaoqing, et al.
Publicado: (2021)

PDS5B inhibits cell proliferation, migration, and invasion via upregulation of LATS1 in lung cancer cells
por: Xu, Hui, et al.
Publicado: (2021)

Author correction to “The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway” [Acta Pharm Sin B 12 (2022) 1288–1304]
por: Ye, Geni, et al.
Publicado: (2023)

Reversible Inhibition of Iron Oxide Nanozyme by Guanidine Chloride
por: Mo, Wei-chuan, et al.
Publicado: (2020)

AUV Positioning Method Based on Tightly Coupled SINS/LBL for Underwater Acoustic Multipath Propagation
por: Zhang, Tao, et al.
Publicado: (2016)

Sin margen y sin fecha
por: Marqués Ravelo, Bernardo, 1947-
Publicado: (1986)

Integrated Analysis of Multi-Omics Data to Establish a Hypoxia-Related Prognostic Model in Osteosarcoma
por: Tong, Ye, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1v2buvok2h8qg68vd5tj1pefrq