Co-administration of Anti microRNA-124 and -137 Oligonucleotides Prevents Hippocampal Neural Stem Cell Loss Upon Non-convulsive Seizures

Convulsive seizures promote adult hippocampal neurogenesis (AHN) through a transient activation of neural stem/progenitor cells (NSPCs) in the subgranular zone (SGZ) of the dentate gyrus (DG). However, in a significant population of epilepsy patients, non-convulsive seizures (ncSZ) are observed. The...

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Detalles Bibliográficos
Autores principales: Bielefeld, Pascal, Schouten, Marijn, Meijer, Guido M., Breuk, Marit J., Geijtenbeek, Karlijne, Karayel, Sedef, Tiaglik, Alisa, Vuuregge, Anna H., Willems, Ruth A.L., Witkamp, Diede, Lucassen, Paul J., Encinas, Juan M., Fitzsimons, Carlos P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389789/
https://www.ncbi.nlm.nih.gov/pubmed/30837840
http://dx.doi.org/10.3389/fnmol.2019.00031

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