Cargando…

Abnormal inhibition of osteoclastogenesis by mesenchymal stem cells through the miR-4284/CXCL5 axis in ankylosing spondylitis

Ankylosing spondylitis (AS) is a common inflammatory autoimmune disease, characterized by pathological osteogenesis. Mesenchymal stem cells (MSCs), as the main source of osteoblasts, participate in bone remodeling not only through differentiation into osteoblasts but also through indirect regulation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Wenjie, Wang, Peng, Xie, Zhongyu, Wang, Shan, Ma, Mengjun, Li, Jinteng, Li, Ming, Cen, Shuizhong, Tang, Su’an, Zheng, Guan, Ye, Guiwen, Wu, Xiaohua, Wu, Yanfeng, Shen, Huiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389901/ https://www.ncbi.nlm.nih.gov/pubmed/30804325 http://dx.doi.org/10.1038/s41419-019-1448-x

Ejemplares similares

Enhanced osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis: a study based on a three-dimensional biomimetic environment
por: Zheng, Guan, et al.
Publicado: (2019)

Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis
por: Ye, Guiwen, et al.
Publicado: (2020)

Interleukin-6/interleukin-6 receptor complex promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells
por: Xie, Zhongyu, et al.
Publicado: (2018)

TNF-α-mediated m(6)A modification of ELMO1 triggers directional migration of mesenchymal stem cell in ankylosing spondylitis
por: Xie, Zhongyu, et al.
Publicado: (2021)

Autophagy enhances mesenchymal stem cell-mediated CD4(+) T cell migration and differentiation through CXCL8 and TGF-β1
por: Cen, Shuizhong, et al.
Publicado: (2019)

Increased BMPR1A Expression Enhances the Adipogenic Differentiation of Mesenchymal Stem Cells in Patients with Ankylosing Spondylitis
por: Liu, Zhenhua, et al.
Publicado: (2019)

Elevated TRAF4 expression impaired LPS-induced autophagy in mesenchymal stem cells from ankylosing spondylitis patients
por: Li, Jinteng, et al.
Publicado: (2017)

TRAF4 positively regulates the osteogenic differentiation of mesenchymal stem cells by acting as an E3 ubiquitin ligase to degrade Smurf2
por: Li, Jinteng, et al.
Publicado: (2019)

TNF-α Induced the Enhanced Apoptosis of Mesenchymal Stem Cells in Ankylosing Spondylitis by Overexpressing TRAIL-R2
por: Liu, Zhenhua, et al.
Publicado: (2017)

LncRNA‐OG Promotes the Osteogenic Differentiation of Bone Marrow‐Derived Mesenchymal Stem Cells Under the Regulation of hnRNPK
por: Tang, Su'an, et al.
Publicado: (2018)

GAS5 protects against osteoporosis by targeting UPF1/SMAD7 axis in osteoblast differentiation
por: Li, Ming, et al.
Publicado: (2020)

Long noncoding RNA repressor of adipogenesis negatively regulates the adipogenic differentiation of mesenchymal stem cells through the hnRNP A1‐PTX3‐ERK axis
por: Pan, Yiqian, et al.
Publicado: (2020)

The N(6)-methyladenosine demethylase ALKBH5 negatively regulates the osteogenic differentiation of mesenchymal stem cells through PRMT6
por: Li, Zhaofeng, et al.
Publicado: (2021)

Aberrantly Expressed lncRNAs and mRNAs of Osteogenically Differentiated Mesenchymal Stem Cells in Ossification of the Posterior Longitudinal Ligament
por: Cai, Zhaopeng, et al.
Publicado: (2020)

LncRNA‐mRNA expression profiles and functional networks in osteoclast differentiation
por: Liu, Wenjie, et al.
Publicado: (2020)

A novel Anti-ROS osteoblast-specific delivery system for ankylosing spondylitis treatment via suppression of both inflammation and pathological new bone formation
por: Zheng, Guan, et al.
Publicado: (2023)

IRF2‐mediated upregulation of lncRNA HHAS1 facilitates the osteogenic differentiation of bone marrow‐derived mesenchymal stem cells by acting as a competing endogenous RNA
por: Ye, Guiwen, et al.
Publicado: (2021)

lncRNA-mRNA expression profiles and functional networks of mesenchymal stromal cells involved in monocyte regulation
por: Li, Ming, et al.
Publicado: (2019)

Autophagy-Mediated Activation of Mucosal-Associated Invariant T Cells Driven by Mesenchymal Stem Cell-Derived IL-15
por: Ye, Guiwen, et al.
Publicado: (2021)

The long noncoding RNA GAS5 negatively regulates the adipogenic differentiation of MSCs by modulating the miR-18a/CTGF axis as a ceRNA
por: Li, Ming, et al.
Publicado: (2018)

SMAD‐specific E3 ubiquitin ligase 2 promotes angiogenesis by facilitating PTX3 degradation in MSCs from patients with ankylosing spondylitis
por: Ma, Mengjun, et al.
Publicado: (2021)

Whole Genome Expression Profiling and Signal Pathway Screening of MSCs in Ankylosing Spondylitis
por: Li, Yuxi, et al.
Publicado: (2014)

α2-HS Glycoprotein in Plasma Extracellular Vesicles Inhibits the Osteogenic Differentiation of Human Mesenchymal Stromal Cells In Vitro
por: Wu, Xiaohua, et al.
Publicado: (2019)

Ankylosing Spondylitis and Cardiac Abnormalities
por: Yang, Dong Heon
Publicado: (2012)

ATF6 aggravates angiogenesis-osteogenesis coupling during ankylosing spondylitis by mediating FGF2 expression in chondrocytes
por: Ma, Mengjun, et al.
Publicado: (2021)

All-Trans Retinoic Acid Improves the Effects of Bone Marrow-Derived Mesenchymal Stem Cells on the Treatment of Ankylosing Spondylitis: An In Vitro Study
por: Li, Deng, et al.
Publicado: (2015)

TRAF4 acts as a fate checkpoint to regulate the adipogenic differentiation of MSCs by activating PKM2
por: Cen, Shuizhong, et al.
Publicado: (2020)

Effects of long-term culture on the biological characteristics and RNA profiles of human bone-marrow-derived mesenchymal stem cells
por: Wang, Shan, et al.
Publicado: (2021)

Alpinetin alleviates osteoporosis by promoting osteogenic differentiation in BMSCs by triggering autophagy via PKA/mTOR/ULK1 signaling
por: Zeng, Chenying, et al.
Publicado: (2022)

Aberrant lncRNA–mRNA expression profile and function networks during the adipogenesis of mesenchymal stem cells from patients with ankylosing spondylitis
por: Cen, Shuizhong, et al.
Publicado: (2022)

Single-cell RNA sequencing analysis of human bone-marrow-derived mesenchymal stem cells and functional subpopulation identification
por: Xie, Zhongyu, et al.
Publicado: (2022)

Ankylosing spondylitis
Publicado: (1980)

Ankylosing spondylitis
por: Edavalath, Mukesh
Publicado: (2010)

Ankylosing Spondylitis
por: Whitfield, A. G. W.
Publicado: (1976)

Ankylosing Spondylitis
por: Ebrahimiadib, Nazanin, et al.
Publicado: (2021)

Mechanism of Hip Arthropathy in Ankylosing Spondylitis: Abnormal Myeloperoxidase and Phagosome
por: Yu, Chaojie, et al.
Publicado: (2021)

Variations in the Gut Microbiota in Breast Cancer Occurrence and Bone Metastasis
por: Wenhui, Yu, et al.
Publicado: (2022)

Andersson Lesion in Ankylosing Spondylitis
por: Wu, Xin, et al.
Publicado: (2022)

Osteogenic differentiation of mesenchymal stem cells promotes c-Jun-dependent secretion of interleukin 8 and mediates the migration and differentiation of CD4(+) T cells
por: Ye, Feng, et al.
Publicado: (2022)

ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression
por: Ye, Guiwen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_clqc0gfjafo2f97kbeksojhsae