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Glycine decarboxylase induces autophagy and is downregulated by miRNA-30d-5p in hepatocellular carcinoma

Glycine decarboxylase (GLDC) belongs to the glycine cleavage system and is involved in one-carbon metabolism. We previously reported that GLDC downregulation enhances hepatocellular carcinoma (HCC) progression and intrahepatic metastasis through decreasing ROS-mediated ubiquitination of cofilin. The...

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Detalles Bibliográficos
Autores principales: Zhuang, Hao, Wu, Fei, Wei, Wen, Dang, Yamei, Yang, Baicai, Ma, Xuda, Han, Feng, Li, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389915/
https://www.ncbi.nlm.nih.gov/pubmed/30804330
http://dx.doi.org/10.1038/s41419-019-1446-z

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