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Structure of amyloid β(25–35) in lipid environment and cholesterol-dependent membrane pore formation
The amyloid β (Aβ) peptide and its shorter variants, including a highly cytotoxic Aβ(25–35) peptide, exert their neurotoxic effect during Alzheimer’s disease by various mechanisms, including cellular membrane permeabilization. The intrinsic polymorphism of Aβ has prevented the identification of the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389947/ https://www.ncbi.nlm.nih.gov/pubmed/30804528 http://dx.doi.org/10.1038/s41598-019-38749-7 |