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A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids

Tumor organoids maintain cell–cell interactions, heterogeneity, microenvironment, and drug response of the sample they originate from. Thus, there is increasing interest in developing tumor organoid models for drug development and personalized medicine applications. Although organoids are in princip...

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Detalles Bibliográficos
Autores principales: Phan, Nhan, Hong, Jenny J., Tofig, Bobby, Mapua, Matthew, Elashoff, David, Moatamed, Neda A., Huang, Jin, Memarzadeh, Sanaz, Damoiseaux, Robert, Soragni, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389967/
https://www.ncbi.nlm.nih.gov/pubmed/30820473
http://dx.doi.org/10.1038/s42003-019-0305-x