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By-Products of Heparin Production Provide a Diverse Source of Heparin-like and Heparan Sulfate Glycosaminoglycans
Global production of pharmaceutical heparin (Hp) is increasing, and the production process from raw mucosal material results in large amounts of waste by-products. These contain lower sulfated Hp-like and heparan sulfate (HS), as well as other glycosaminoglycans, which are bioactive entities with ph...
Autores principales: | Taylor, Sarah L., Hogwood, John, Guo, Wei, Yates, Edwin A., Turnbull, Jeremy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389988/ https://www.ncbi.nlm.nih.gov/pubmed/30804383 http://dx.doi.org/10.1038/s41598-019-39093-6 |
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