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Cholesterol bound Plasmodium falciparum co-chaperone ‘PFA0660w’ complexes with major virulence factor ‘PfEMP1’ via chaperone ‘PfHsp70-x’

Lethality of Plasmodium falciparum caused malaria results from ‘cytoadherence’, which is mainly effected by exported Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family. Several exported P. falciparum proteins (exportome) including chaperones alongside cholesterol rich microdomains...

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Detalles Bibliográficos
Autores principales: Behl, Ankita, Kumar, Vikash, Bisht, Anjali, Panda, Jiban J., Hora, Rachna, Mishra, Prakash Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389991/
https://www.ncbi.nlm.nih.gov/pubmed/30804381
http://dx.doi.org/10.1038/s41598-019-39217-y

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