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Combination leflunomide and methotrexate impedes the recovery of liver fibrosis, partly through inhibition of myeloid cell admittance

The process of liver fibrosis is reversible and involves a recovery phase. In the present study, the potential side effects of combination leflunomide and methotrexate (LEF+MTX), a conventional rheumatoid arthritis therapy used in the resolution of liver fibrosis, was investigated. In a carbon tetra...

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Detalles Bibliográficos
Autores principales: Lin, Mengxin, Guo, Ruyi, Su, Zhijun, Ke, Shaopeng, Zeng, Dawu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390013/
https://www.ncbi.nlm.nih.gov/pubmed/30628675
http://dx.doi.org/10.3892/mmr.2019.9821