Cargando…

Novel 1,4-naphthoquinone derivatives induce reactive oxygen species-mediated apoptosis in liver cancer cells

Derivatives of 1,4-naphthoquinone have excellent anti-cancer effects, but their use has been greatly limited due to their serious side effects. To develop compounds with decreased side effects and improved anti-cancer activity, two novel types of 1,4-naphthoquinone derivatives, 2,3-dihydro-2,3-epoxy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yue, Luo, Ying-Hua, Piao, Xian-Ji, Shen, Gui-Nan, Meng, Ling-Qi, Zhang, Yi, Wang, Jia-Ru, Li, Jin-Qian, Wang, Hao, Xu, Wan-Ting, Liu, Yang, Zhang, Yu, Zhang, Tong, Wang, Shi-Nong, Sun, Hu-Nan, Han, Ying-Hao, Jin, Mei-Hua, Zang, Yan-Qing, Zhang, Dong-Jie, Jin, Cheng-Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390020/ https://www.ncbi.nlm.nih.gov/pubmed/30592276 http://dx.doi.org/10.3892/mmr.2018.9785

Ejemplares similares

Two novel 1,4-naphthoquinone derivatives induce human gastric cancer cell apoptosis and cell cycle arrest by regulating reactive oxygen species-mediated MAPK/Akt/STAT3 signaling pathways
por: Wang, Hao, et al.
Publicado: (2019)

2-(6-Hydroxyhexylthio)-5,8-dimethoxy-1,4-naphthoquinone Induces Apoptosis through ROS-Mediated MAPK, STAT3, and NF-κB Signalling Pathways in Lung Cancer A549 Cells
por: Shen, Gui-Nan, et al.
Publicado: (2020)

Quinalizarin Induces Apoptosis through Reactive Oxygen Species (ROS)-Mediated Mitogen-Activated Protein Kinase (MAPK) and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathways in Colorectal Cancer Cells
por: Meng, Ling-Qi, et al.
Publicado: (2018)

2-cyclohexylamino-5,8-dimethoxy-1,4-naphthoquinone inhibits LPS-induced BV2 microglial activation through MAPK/NF-kB signaling pathways
por: Sun, Hu-Nan, et al.
Publicado: (2016)

The compound 2-benzylthio-5,8-dimethoxynaphthalene-1,4-dione leads to apoptotic cell death by increasing the cellular reactive oxygen species levels in Ras-mutated liver cancer cells
por: Shen, Gui-Nan, et al.
Publicado: (2020)

Cryptotanshinone induces ROS-mediated apoptosis in human gastric cancer cells
por: Liu, Chang, et al.
Publicado: (2017)

Novel 2-Amino-1,4-Naphthoquinone Derivatives Induce A549 Cell Death through Autophagy
por: Tan, Hua-Yuan, et al.
Publicado: (2023)

18β-Glycyrrhetinic Acid Has Anti-Cancer Effects via Inducing Apoptosis and G2/M Cell Cycle Arrest, and Inhibiting Migration of A549 Lung Cancer Cells
por: Luo, Ying-Hua, et al.
Publicado: (2021)

Zeaxanthin Induces Apoptosis via ROS-Regulated MAPK and AKT Signaling Pathway in Human Gastric Cancer Cells
por: Sheng, Ya-Nan, et al.
Publicado: (2020)

Sanguinarine induces apoptosis in Eimeria tenella sporozoites via the generation of reactive oxygen species
por: Li, Jun-Yi, et al.
Publicado: (2022)

Peroxiredoxin II Maintains the Mitochondrial Membrane Potential against Alcohol-Induced Apoptosis in HT22 Cells
por: Jin, Mei-Hua, et al.
Publicado: (2019)

Near‐Infrared Chemiluminescent Carbon Nanodots and Their Application in Reactive Oxygen Species Bioimaging
por: Shen, Cheng‐Long, et al.
Publicado: (2020)

1,4-Naphthoquinone Analogues: Potent Antibacterial Agents and Mode of Action Evaluation
por: Ravichandiran, Palanisamy, et al.
Publicado: (2019)

A Survey on the Reactivity of Phenyliodonium Ylide of 2-Hydroxy-1,4-Naphthoquinone with Amino Compounds
por: Spagou, Konstantina, et al.
Publicado: (2005)

Synthesis and Biological Evaluation of Novel 2-Amino-1,4-Naphthoquinone Amide-Oxime Derivatives as Potent IDO1/STAT3 Dual Inhibitors with Prospective Antitumor Effects
por: Huang, Ri-Zhen, et al.
Publicado: (2023)

Organocatalytic asymmetric Michael addition of unprotected 3-substituted oxindoles to 1,4-naphthoquinone
por: Yu, Jin-Sheng, et al.
Publicado: (2012)

Cytotoxicity of naphthoquinones and their capacity to generate reactive oxygen species is quenched when conjugated with gold nanoparticles
por: Srinivas, Priya, et al.
Publicado: (2011)

Peroxiredoxin I deficiency increases pancreatic β-cell apoptosis after streptozotocin stimulation via the AKT/GSK3β signaling pathway
por: Jin, Mei-Hua, et al.
Publicado: (2020)

Lactate dehydrogenases amplify reactive oxygen species in cancer cells in response to oxidative stimuli
por: Wu, Hao, et al.
Publicado: (2021)

Quinalizarin induces ROS-mediated apoptosis via the MAPK, STAT3 and NF-κB signaling pathways in human breast cancer cells
por: Zang, Yan-Qing, et al.
Publicado: (2019)

Synthesis and Antimicrobial Evaluation of 1,4‐Naphthoquinone Derivatives as Potential Antibacterial Agents
por: Ravichandiran, Palanisamy, et al.
Publicado: (2019)

B(C(6)F(5))(3)-Catalyzed C–C Coupling of 1,4-Naphthoquinones with the C-3 Position of Indole Derivatives in Water
por: Dong, Yu, et al.
Publicado: (2019)

Synthesis and Biological Evaluation of Lipophilic 1,4-Naphthoquinone Derivatives against Human Cancer Cell Lines
por: Wang, Shao-Hung, et al.
Publicado: (2015)

Advanced Biomedical Applications of Reactive Oxygen Species-Based Nanomaterials in Lung Cancer
por: Zhao, Nan, et al.
Publicado: (2021)

Engeletin Protects Against TNF-α-Induced Apoptosis and Reactive Oxygen Species Generation in Chondrocytes and Alleviates Osteoarthritis in vivo
por: Wang, Hao, et al.
Publicado: (2021)

Removal of 1,4-Naphthoquinone by Birnessite-Catalyzed Oxidation: Effect of Phenolic Mediators and the Reaction Pathway
por: Lee, Han-Saem, et al.
Publicado: (2020)

5-Hydroxy-8-nitro-1,4-naphthoquinone
por: Tan, Daniel Teoh-Chuan, et al.
Publicado: (2008)

TIGAR contributes to ischemic tolerance induced by cerebral preconditioning through scavenging of reactive oxygen species and inhibition of apoptosis
por: Zhou, Jun-Hao, et al.
Publicado: (2016)

Depletion of peroxiredoxin II promotes keratinocyte apoptosis and alleviates psoriatic skin lesions via the PI3K/AKT/GSK3β signaling axis
por: Han, Ying-Hao, et al.
Publicado: (2023)

Neuronal nitric oxide synthase/reactive oxygen species pathway is involved in apoptosis and pyroptosis in epilepsy
por: Xu, Xiao-Xue, et al.
Publicado: (2022)

Ionizing Radiation Upregulates Glutamine Metabolism and Induces Cell Death via Accumulation of Reactive Oxygen Species
por: Yang, Pengfei, et al.
Publicado: (2021)

Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis
por: Su, Lian-Jiu, et al.
Publicado: (2019)

Label-Free Proteomic Analysis of Molecular Effects of 2-Methoxy-1,4-naphthoquinone on Penicillium italicum
por: Guo, Meixia, et al.
Publicado: (2019)

Formation of 5-Hydroxy-3-methoxy-1,4-naphthoquinone and 8-Hydroxy-4-methoxy-1,2-naphthoquinone from Juglone
por: Blauenburg, Bastian, et al.
Publicado: (2012)

Ascorbic Acid Sensitizes Colorectal Carcinoma to the Cytotoxicity of Arsenic Trioxide via Promoting Reactive Oxygen Species-Dependent Apoptosis and Pyroptosis
por: Tian, Wei, et al.
Publicado: (2020)

Peroxiredoxin II with dermal mesenchymal stem cells accelerates wound healing
por: Jin, Mei-Hua, et al.
Publicado: (2021)

Involvement of reactive oxygen species in lanthanum-induced inhibition of primary root growth
por: Liu, Yang-Yang, et al.
Publicado: (2016)

2-Chloro-3-(4-chlorobenzamido)-1,4-naphthoquinone
por: Brandy, Yakini, et al.
Publicado: (2008)

Aromatase inhibitory activity of 1,4-naphthoquinone derivatives and QSAR study
por: Prachayasittikul, Veda, et al.
Publicado: (2017)

Cyanidin-3-O-Glucoside Induces the Apoptosis of Human Gastric Cancer MKN-45 Cells through ROS-Mediated Signaling Pathways
por: Sun, Wei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6sg6rh17sd0idtdrkdvjmt76es