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Febuxostat inhibits TGF-β1-induced epithelial-mesenchymal transition via downregulation of USAG-1 expression in Madin-Darby canine kidney cells in vitro

Our previous study demonstrated that febuxostat, a xanthine oxidase inhibitor, can alleviate kidney dysfunction and ameliorate renal tubulointerstitial fibrosis in a rat unilateral ureteral obstruction (UUO) model; however, the underlying mechanisms remain unknown. Increasing evidence has revealed t...

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Detalles Bibliográficos
Autores principales:	Lu, Linghong, Zhu, Jiajun, Zhang, Yaqian, Wang, Yanxia, Zhang, Shu, Xia, Anzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390060/ https://www.ncbi.nlm.nih.gov/pubmed/30628645 http://dx.doi.org/10.3892/mmr.2019.9806

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