Beta2-Adrenergic Receptor Polymorphisms and Haplotypes Associate With Chronic Pain in Sickle Cell Disease

Pain in sickle cell disease (SCD) is severe, variable, and inadequately comprehended. The β2-adrenergic receptor (ADRB2) is critical in mediating neurotransmitter response in the sympathetic nervous system. In this association study, we examined 16 single nucleotide polymorphisms (SNPs) covering 5′-...

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Detalles Bibliográficos
Autores principales: Jhun, Ellie H., Sadhu, Nilanjana, Hu, Xiaoyu, Yao, Yingwei, He, Ying, Wilkie, Diana J., Molokie, Robert E., Wang, Zaijie Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390066/
https://www.ncbi.nlm.nih.gov/pubmed/30837870
http://dx.doi.org/10.3389/fphar.2019.00084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390066/
https://www.ncbi.nlm.nih.gov/pubmed/30837870
http://dx.doi.org/10.3389/fphar.2019.00084

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