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Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics

Nephrons scar and involute during aging, increasing the risk of chronic kidney disease. Little is known, however, about genetic mechanisms of kidney aging. We sought to define the signatures of age on the renal transcriptome using 563 human kidneys. The initial discovery analysis of 260 kidney trans...

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Detalles Bibliográficos
Autores principales:	Rowland, Joshua, Akbarov, Artur, Eales, James, Xu, Xiaoguang, Dormer, John P., Guo, Hui, Denniff, Matthew, Jiang, Xiao, Ranjzad, Parisa, Nazgiewicz, Alicja, Prestes, Priscilla Ribeiro, Antczak, Andrzej, Szulinska, Monika, Wise, Ingrid A., Zukowska-Szczechowska, Ewa, Bogdanski, Pawel, Woolf, Adrian S., Samani, Nilesh J., Charchar, Fadi J., Tomaszewski, Maciej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390171/ https://www.ncbi.nlm.nih.gov/pubmed/30784661 http://dx.doi.org/10.1016/j.kint.2018.10.029

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