Cargando…

Targeting Immune-Related Molecules in Cancer Therapy: A Comprehensive In Vitro Analysis on Patient-Derived Tumor Models

This study investigated the impact of immune-related pathway inhibition, among them indolamine 2,3-dioxygenase (IDO), alone and together with immune cells on growth and viability of colorectal cancer (CRC) cells. A panel of patient-derived CRC cell lines with different molecular characteristics (CpG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maletzki, Claudia, Scheinpflug, Philine, Witt, Anika, Klar, Ernst, Linnebacher, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390245/ https://www.ncbi.nlm.nih.gov/pubmed/30891459 http://dx.doi.org/10.1155/2019/4938285

Ejemplares similares

Bacterial immunotherapy of gastrointestinal tumors
por: Linnebacher, Michael, et al.
Publicado: (2011)

The mutational profile and infiltration pattern of murine MLH1(-/-) tumors: concurrences, disparities and cell line establishment for functional analysis
por: Maletzki, Claudia, et al.
Publicado: (2016)

Functional Characterization and Drug Response of Freshly Established Patient-Derived Tumor Models with CpG Island Methylator Phenotype
por: Maletzki, Claudia, et al.
Publicado: (2015)

Host defense peptides for treatment of colorectal carcinoma – a comparative in vitro and in vivo analysis
por: Maletzki, Claudia, et al.
Publicado: (2014)

Murine Endogenous Retroviruses Are Detectable in Patient-Derived Xenografts but Not in Patient-Individual Cell Lines of Human Colorectal Cancer
por: Bock, Stephanie, et al.
Publicado: (2018)

Ex-vivo Clonally Expanded B Lymphocytes Infiltrating Colorectal Carcinoma Are of Mature Immunophenotype and Produce Functional IgG
por: Maletzki, Claudia, et al.
Publicado: (2012)

Tumor-infiltrating B cells: The ignored players in tumor immunology
por: Linnebacher, Michael, et al.
Publicado: (2012)

Cryopreservation of human colorectal carcinomas prior to xenografting
por: Linnebacher, Michael, et al.
Publicado: (2010)

Microsatellite instability in hematological malignancies: Hypermutation vs. immune control—who is challenging who?
por: Maletzki, Claudia, et al.
Publicado: (2013)

An MSI Tumor Specific Frameshift Mutation in a Coding Microsatellite of MSH3 Encodes for HLA-A0201-Restricted CD8(+) Cytotoxic T Cell Epitopes
por: Garbe, Yvette, et al.
Publicado: (2011)

Multidrug-resistance proteins are weak tumor associated antigens for colorectal carcinoma
por: Mullins, Christina S, et al.
Publicado: (2011)

Biological and Molecular Effects of Small Molecule Kinase Inhibitors on Low-Passage Human Colorectal Cancer Cell Lines
por: Lange, Falko, et al.
Publicado: (2014)

Tumor Take Rate Optimization for Colorectal Carcinoma Patient-Derived Xenograft Models
por: Gock, Michael, et al.
Publicado: (2016)

Identification of an MSI-H Tumor-Specific Cytotoxic T Cell Epitope Generated by the (−1) Frame of U79260(FTO)
por: Linnebacher, Michael, et al.
Publicado: (2010)

HGG-07. CYCLIN-DEPENDENT KINASES AS TARGET STRUCTURES FOR CANCER THERAPY – A COMPARATIVE IN VITRO ANALYSIS ON PATIENT-DERIVED GLIOBLASTOMA CELL CULTURE MODELS
por: Riess, Christin, et al.
Publicado: (2020)

Combinations of TLR Ligands: A Promising Approach in Cancer Immunotherapy
por: Stier, Saskia, et al.
Publicado: (2013)

Reevaluating the Concept of Treating Experimental Tumors with a Mixed Bacterial Vaccine: Coley's Toxin
por: Maletzki, C., et al.
Publicado: (2012)

Colorectal carcinoma tumour budding and podia formation in the xenograft microenvironment
por: Prall, Friedrich, et al.
Publicado: (2017)

Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line
por: Gock, Michael, et al.
Publicado: (2018)

Optimizing the process of nucleofection for professional antigen presenting cells
por: Mullins, Christina Susanne, et al.
Publicado: (2015)

Establishment and characterization of HROC69 – a Crohn´s related colonic carcinoma cell line and its matched patient-derived xenograft
por: Kuehn, Florian, et al.
Publicado: (2016)

Establishment, Characterization and Chemosensitivity of Three Mismatch Repair Deficient Cell Lines from Sporadic and Inherited Colorectal Carcinomas
por: Maletzki, Claudia, et al.
Publicado: (2012)

Integrated Biobanking and Tumor Model Establishment of Human Colorectal Carcinoma Provides Excellent Tools for Preclinical Research
por: Mullins, Christina S., et al.
Publicado: (2019)

Establishment, functional and genetic characterization of three novel patient-derived rectal cancer cell lines
por: Gock, Michael, et al.
Publicado: (2018)

A novel sialyl Le(X) expression score as a potential prognostic tool in colorectal cancer
por: Schiffmann, Leif, et al.
Publicado: (2012)

Cancer-Cell-Derived IgG and Its Potential Role in Tumor Development
por: Kdimati, Said, et al.
Publicado: (2021)

In vivo vaccination with cell line-derived whole tumor lysates: neoantigen quality, not quantity matters
por: Salewski, Inken, et al.
Publicado: (2020)

Inflammatory Bowel Diseases: Current Medical and Surgical Therapy
por: Neurath, Markus F., et al.
Publicado: (2015)

Increased SEC23A Expression Correlates with Poor Prognosis and Immune Infiltration in Stomach Adenocarcinoma †
por: Zhaoran, Su, et al.
Publicado: (2023)

Nanobodies targeting immune checkpoint molecules for tumor immunotherapy and immunoimaging (Review)
por: Yu, Sheng, et al.
Publicado: (2021)

The future of immune checkpoint combinations with tumor-targeted small molecule drugs
por: Sceneay, Jaclyn, et al.
Publicado: (2021)

Combined vaccine-immune-checkpoint inhibition constitutes a promising strategy for treatment of dMMR tumors
por: Salewski, Inken, et al.
Publicado: (2021)

Establishment, characterization, and drug screening of low-passage patient individual non-small cell lung cancer in vitro models including the rare pleomorphic subentity
por: Andus, Ingo, et al.
Publicado: (2023)

Comprehensive Genomic Profiling of Rare Tumors: Routes to Targeted Therapies
por: Wang, Shuhang, et al.
Publicado: (2020)

Temozolomide-induced increase of tumorigenicity can be diminished by targeting of mitochondria in in vitro models of patient individual glioblastoma
por: William, Doreen, et al.
Publicado: (2018)

Comprehensive in vitro characterization of PD-L1 small molecule inhibitors
por: Ganesan, Aravindhan, et al.
Publicado: (2019)

Alteration of DSS-mediated immune cell redistribution in murine colitis by oral colostral immunoglobulin
por: Bodammer, Peggy, et al.
Publicado: (2013)

Antisense oligonucleotide targeting CD39 improves anti-tumor T cell immunity
por: Kashyap, Abhishek S., et al.
Publicado: (2019)

Targeted Tumor Therapy Remixed—An Update on the Use of Small-Molecule Drugs in Combination Therapies
por: Gatzka, Martina V.
Publicado: (2018)

Novel harmine derivatives for tumor targeted therapy
por: Li, Siwen, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_jgoedpav193tl9abfojc205m71