Cargando…

Stem cells: past, present, and future

In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the discovery of different stem cells and the potential therapies based on these cells. The gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Zakrzewski, Wojciech, Dobrzyński, Maciej, Szymonowicz, Maria, Rybak, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390367/
https://www.ncbi.nlm.nih.gov/pubmed/30808416
http://dx.doi.org/10.1186/s13287-019-1165-5
_version_ 1783398129903599616
author Zakrzewski, Wojciech
Dobrzyński, Maciej
Szymonowicz, Maria
Rybak, Zbigniew
author_facet Zakrzewski, Wojciech
Dobrzyński, Maciej
Szymonowicz, Maria
Rybak, Zbigniew
author_sort Zakrzewski, Wojciech
collection PubMed
description In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the discovery of different stem cells and the potential therapies based on these cells. The genesis of stem cells is followed by laboratory steps of controlled stem cell culturing and derivation. Quality control and teratoma formation assays are important procedures in assessing the properties of the stem cells tested. Derivation methods and the utilization of culturing media are crucial to set proper environmental conditions for controlled differentiation. Among many types of stem tissue applications, the use of graphene scaffolds and the potential of extracellular vesicle-based therapies require attention due to their versatility. The review is summarized by challenges that stem cell therapy must overcome to be accepted worldwide. A wide variety of possibilities makes this cutting edge therapy a turning point in modern medicine, providing hope for untreatable diseases.
format Online
Article
Text
id pubmed-6390367
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-63903672019-03-19 Stem cells: past, present, and future Zakrzewski, Wojciech Dobrzyński, Maciej Szymonowicz, Maria Rybak, Zbigniew Stem Cell Res Ther Review In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations. This paper is a review focused on the discovery of different stem cells and the potential therapies based on these cells. The genesis of stem cells is followed by laboratory steps of controlled stem cell culturing and derivation. Quality control and teratoma formation assays are important procedures in assessing the properties of the stem cells tested. Derivation methods and the utilization of culturing media are crucial to set proper environmental conditions for controlled differentiation. Among many types of stem tissue applications, the use of graphene scaffolds and the potential of extracellular vesicle-based therapies require attention due to their versatility. The review is summarized by challenges that stem cell therapy must overcome to be accepted worldwide. A wide variety of possibilities makes this cutting edge therapy a turning point in modern medicine, providing hope for untreatable diseases. BioMed Central 2019-02-26 /pmc/articles/PMC6390367/ /pubmed/30808416 http://dx.doi.org/10.1186/s13287-019-1165-5 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Zakrzewski, Wojciech
Dobrzyński, Maciej
Szymonowicz, Maria
Rybak, Zbigniew
Stem cells: past, present, and future
title Stem cells: past, present, and future
title_full Stem cells: past, present, and future
title_fullStr Stem cells: past, present, and future
title_full_unstemmed Stem cells: past, present, and future
title_short Stem cells: past, present, and future
title_sort stem cells: past, present, and future
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390367/
https://www.ncbi.nlm.nih.gov/pubmed/30808416
http://dx.doi.org/10.1186/s13287-019-1165-5
work_keys_str_mv AT zakrzewskiwojciech stemcellspastpresentandfuture
AT dobrzynskimaciej stemcellspastpresentandfuture
AT szymonowiczmaria stemcellspastpresentandfuture
AT rybakzbigniew stemcellspastpresentandfuture